Single‐dose, placebo‐controlled, randomized study of AMG 785, a sclerostin monoclonal antibody - Padhi, Desmond; Jang, Graham; Stouch, Brian; Fang, Liang; Posvar, Edward (Journal of bone and mineral research, 2011)
Keywords: AMG 785; ANABOLIC; Antibodies, Monoclonal - adverse effects; Antibodies, Monoclonal - blood; Antibodies, Monoclonal - pharmacokinetics; Antibodies, Monoclonal - pharmacology; Biological and medical sciences; Biomarkers - metabolism; Bone and Bones - drug effects; Bone and Bones - metabolism; Bone Density - drug effects; BONE FORMATION; Bone Morphogenetic Proteins - immunology; Bone Remodeling - drug effects; Demography; Dose-Response Relationship, Drug; Female; Fundamental and applied biological sciences. Psychology; Genetic Markers - immunology; Humans; Male; Middle Aged; Placebos; SCLEROSTIN ANTIBODY; Skeleton and joints; Time Factors; Vertebrates: osteoarticular system, musculoskeletal system; Osteoarticular system; ANABOLIC; Vertebrata; Mammalia; SCLEROSTIN ANTIBODY; Single dose; BONE FORMATION; Monoclonal antibody; Bone; Formation; AMG 785