A prospective microbiome‐wide association study of food sensitization and food allergy in early childhood

• Published in: Allergy (Copenhagen) Vol. 73; no. 1; pp. 145 - 152
• Main Authors: Savage, Jessica H., Lee‐Sarwar, Kathleen A., Sordillo, Joanne, Bunyavanich, Supinda, Zhou, Yanjiao, O'Connor, George, Sandel, Megan, Bacharier, Leonard B., Zeiger, Robert, Sodergren, Erica, Weinstock, George M., Gold, Diane R., Weiss, Scott T., Litonjua, Augusto A.
• Format: Journal Article
• Language: English
• Published: Denmark Blackwell Publishing Ltd 01.01.2018
• Subjects: Age; Allergens - immunology; Asthma; Biodiversity; Child, Preschool; Childhood; Children; Colonization; Dorea; Female; Food allergies; food allergy; Food Hypersensitivity - epidemiology; Food Hypersensitivity - immunology; food sensitization; Gastrointestinal Microbiome; Humans; Immunization; Immunoglobulin E; Immunoglobulin E - immunology; Intestine; Male; Metagenome; Metagenomics - methods; microbiome; Microbiota - immunology; Milk; Pregnancy; Vitamin D; Dorea; food allergy; microbiome; food sensitization

Background Alterations in the intestinal microbiome are prospectively associated with the development of asthma; less is known regarding the role of microbiome alterations in food allergy development. Methods Intestinal microbiome samples were collected at age 3‐6 months in children participating in...