Roles of the second messenger c‐di‐GMP in bacteria: Focusing on the topics of flagellar regulation and Vibrio spp

• Published in: Genes to cells : devoted to molecular & cellular mechanisms Vol. 27; no. 3; pp. 157 - 172
• Main Authors: Homma, Michio, Kojima, Seiji
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.03.2022; John Wiley and Sons Inc
• Subjects: Bacteria; bacterial flagellum; Bacterial Proteins - genetics; Biodegradation; Biofilms; Cellulose; Cyclic AMP; Cyclic GMP; Cyclic GMP - analogs & derivatives; energy transduction; Escherichia coli Proteins - metabolism; Flagella; Gene Expression Regulation, Bacterial; gene regulation; Inositol phosphate; molecular motor; motility; Review; rotary nano‐machine; Second Messenger Systems - physiology; Second messengers; signal transduction; Vibrio; Vibrio cholerae - metabolism; energy transduction; bacterial flagellum; gene regulation; signal transduction; motility; rotary nano-machine; molecular motor

Typical second messengers include cyclic AMP (cAMP), cyclic GMP (cGMP), and inositol phosphate. In bacteria, cyclic diguanylate (c‐di‐GMP), which is not used in animals, is widely used as a second messenger for environmental responses. Initially found as a regulator of cellulose synthesis, this smal...