A Ketone Ester Drink Lowers Human Ghrelin and Appetite

• Published in: Obesity (Silver Spring, Md.) Vol. 26; no. 2; pp. 269 - 273
• Main Authors: Stubbs, Brianna J., Cox, Pete J., Evans, Rhys D., Cyranka, Malgorzata, Clarke, Kieran, de Wet, Heidi
• Format: Journal Article
• Language: English
• Published: United States 01.02.2018
• Subjects: Adult; Appetite - physiology; Beverages - analysis; Cross-Over Studies; Esters - administration & dosage; Esters - pharmacology; Esters - therapeutic use; Female; Ghrelin - blood; Humans; Hunger - physiology; Ketones - administration & dosage; Ketones - pharmacology; Ketones - therapeutic use; Male; Single-Blind Method; Young Adult

Objective The ketones d‐β‐hydroxybutyrate (BHB) and acetoacetate are elevated during prolonged fasting or during a “ketogenic” diet. Although weight loss on a ketogenic diet may be associated with decreased appetite and altered gut hormone levels, it is unknown whether such changes are caused by ele...