Loop Diuretic Prescription and 30-Day Outcomes in Older Patients With Heart Failure

• Published in: Journal of the American College of Cardiology Vol. 76; no. 6; pp. 669 - 679
• Main Authors: Faselis, Charles, Arundel, Cherinne, Patel, Samir, Lam, Phillip H., Gottlieb, Stephen S., Zile, Michael R., Deedwania, Prakash, Filippatos, Gerasimos, Sheriff, Helen M., Zeng, Qing, Morgan, Charity J., Wopperer, Samuel, Nguyen, Tran, Allman, Richard M., Fonarow, Gregg C., Ahmed, Ali
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 11.08.2020
• Subjects: Aged; Aged, 80 and over; Cardiovascular; Cohort Studies; Female; heart failure; Heart Failure - drug therapy; Humans; loop diuretics; Male; outcomes; Sodium Potassium Chloride Symporter Inhibitors - therapeutic use; Time Factors; Treatment Outcome; heart failure; EF; RCT; outcomes; HFpEF; loop diuretics; HFrEF; HF; heart failure with preserved ejection fraction; ejection fraction; heart failure with reduced ejection fraction; randomized controlled trial

Heart failure (HF) is a major source of morbidity and mortality. Fluid retention and shortness of breath are its cardinal manifestations for which loop diuretics are used. Although their usefulness is well accepted, less is known about their role in improving clinical outcomes. The purpose of this s...