Carnitine Palmitoyltransferase System: A New Target for Anti-Inflammatory and Anticancer Therapy?

• Published in: Frontiers in pharmacology Vol. 12; p. 760581
• Main Authors: Wang, Muyun, Wang, Kun, Liao, Ximing, Hu, Haiyang, Chen, Liangzhi, Meng, Linlin, Gao, Wei, Li, Qiang
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 26.10.2021
• Subjects: cancers; carnitine palmitoyltransferase (CPT); CPT activator; CPT inhibitor; fatty acid oxidation (FAO); inflammatory diseases; Pharmacology

Lipid metabolism involves multiple biological processes. As one of the most important lipid metabolic pathways, fatty acid oxidation (FAO) and its key rate-limiting enzyme, the carnitine palmitoyltransferase (CPT) system, regulate host immune responses and thus are of great clinical significance. Th...