Platelet Indices in Patients with Coal Workers’ Pneumoconiosis

• Published in: Lung Vol. 194; no. 4; pp. 675 - 679
• Main Authors: Uygur, Firat, Ornek, Tacettin, Tanriverdi, Hakan, Altuntas, Murat, Altinsoy, Bulent, Erboy, Fatma, Tor, Meltem, Atalay, Figen
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.08.2016; Springer; Springer Nature B.V
• Subjects: Aged; Anthracosis - blood; Anthracosis - complications; Anthracosis - pathology; Biomarkers - blood; Black lung disease; Blood Platelets; Care and treatment; Coal mining; Demographic aspects; Diagnosis; Disease Progression; Female; Human exposure; Humans; Lung diseases; Male; Mean Platelet Volume; Medicine; Medicine & Public Health; Middle Aged; Occupational Diseases - blood; Occupational Diseases - complications; Occupational Diseases - pathology; Occupational Exposure; Occupational health; Physiological aspects; Platelet Count; Pneumology/Respiratory System; Pulmonary Fibrosis - blood; Pulmonary Fibrosis - etiology; Pulmonary Fibrosis - pathology; Retrospective Studies; Risk factors; Turkey; Reactive oxygen species; Platelet indices; Pneumoconiosis; Coal mine

Purpose Coal workers’ pneumoconiosis (CWP) is caused by an accumulation of coal particles in the lung parenchyma. Reactive oxygen species (ROS) play an important role in the pathogenesis of CWP. It is well documented that ROS stimulate platelet activation, adhesion, and aggregation. The aim of the p...