Elevation of miR-221 and -222 in the internal mammary arteries of diabetic subjects and normalization with metformin - Coleman, Chasity B.; Lightell, Daniel J.; Moss, Stephanie C.; Bates, Michael; Parrino, Patrick E.; Woods, T. Cooper (Molecular and cellular endocrinology, 2013)
Keywords: Aged; Biopsy; cardiovascular diseases; Cardiovascular Diseases - complications; Cardiovascular Diseases - drug therapy; Cardiovascular Diseases - genetics; Cardiovascular Diseases - surgery; Coronary Artery Bypass; coronary vessels; Cross-Sectional Studies; Diabetes; Diabetes Mellitus, Type 2 - complications; Diabetes Mellitus, Type 2 - drug therapy; Diabetes Mellitus, Type 2 - genetics; Diabetes Mellitus, Type 2 - surgery; Female; Gene Expression Regulation; Humans; Hypoglycemic Agents - pharmacology; Internal mammary artery; Male; Mammary Arteries - metabolism; Mammary Arteries - pathology; Mammary Arteries - surgery; messenger RNA; Metformin; Metformin - pharmacology; microRNA; MicroRNAs - antagonists & inhibitors; MicroRNAs - genetics; MicroRNAs - metabolism; Middle Aged; miR-221/222; Muscle, Smooth, Vascular - drug effects; Muscle, Smooth, Vascular - metabolism; Muscle, Smooth, Vascular - pathology; Myocytes, Smooth Muscle - drug effects; Myocytes, Smooth Muscle - metabolism; Myocytes, Smooth Muscle - pathology; Primary Cell Culture; risk factors; smooth muscle; Vascular smooth muscle cell; CVD; AMPK; Vascular smooth muscle cell; VSMC; Diabetes; Metformin; Internal mammary artery; IMA; miR-221/222