Decreased placental expression of pre-adipocyte factor-1 in children born small-for-gestational-age: Association to early postnatal weight gain

• Published in: Placenta (Eastbourne) Vol. 34; no. 4; pp. 331 - 334
• Main Authors: Díaz, M., Bassols, J., Aragonés, G., Mazarico, E., López-Bermejo, A., Ibáñez, L.
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 01.04.2013; Elsevier
• Subjects: Adult; Biological and medical sciences; Body Composition; Child Development; Down-Regulation; Embryology: invertebrates and vertebrates. Teratology; Female; Fetal Development; Fundamental and applied biological sciences. Psychology; Gestational Age; Humans; Infant; Infant, Newborn; Infant, Small for Gestational Age - growth & development; Intercellular Signaling Peptides and Proteins - biosynthesis; Internal Medicine; Male; Membrane Proteins - biosynthesis; Obstetrics and Gynecology; Placenta; Placenta - metabolism; Postnatal weight; Pre-adipocyte factor-1; Pregnancy; Prenatal growth; SGA; Weight Gain; Pre-adipocyte factor-1; Prenatal growth; Placenta; SGA; Postnatal weight; Human; Adipocyte; Intrauterine growth retardation; Pregnancy disorders; Fetal membrane; Low birth weight; Birth; Weight gain; Fetal diseases; Newborn diseases; Vertebrata; Mammalia; Postnatal; Prematurity; Early; Child

Preadipocyte factor-1 (Pref-1) is a key regulator of adipocyte differentiation acting as an inhibitor of adipogenesis; Pref-1 is highly expressed in embryonic tissues and placenta supporting a role in embryonic and fetal growth. The potential impact of placental Pref-1 expression in human pre- and p...