Fetal Growth Restriction Caused by Sexual Transmission of Zika Virus in Mice

• Published in: The Journal of infectious diseases Vol. 215; no. 11; pp. 1720 - 1724
• Main Authors: Uraki, Ryuta, Jurado, Kellie Ann, Hwang, Jesse, Szigeti-Buck, Klara, Horvath, Tamas L., Iwasaki, Akiko, Fikrig, Erol
• Format: Journal Article
• Language: English
• Published: US Oxford University Press 01.06.2017
• Subjects: Animals; Brief Report; Disease Models, Animal; Female; Fetal Growth Retardation - virology; Male; Mice; Pregnancy; Pregnancy Complications, Infectious - virology; Sexually Transmitted Diseases, Viral - transmission; Sexually Transmitted Diseases, Viral - virology; VIRUSES; Zika Virus; Zika Virus Infection - transmission; Zika Virus Infection - virology; fetal growth abnormalities; electron microscopy; Zika virus; sexual transmission

Zika virus (ZIKV) can be transmitted by mosquito bite or sexual contact. Using mice that lack the type I interferon receptor, we examined sexual transmission of ZIKV. Electron microscopy analyses showed association of virions with developing sperm within testes as well as with mature sperm within ep...