A Review of the Novel Application and Potential Adverse Effects of Proton Pump Inhibitors

• Published in: Advances in therapy Vol. 34; no. 5; pp. 1070 - 1086
• Main Authors: Yu, Li-Yuan, Sun, Lu-Ning, Zhang, Xue-Hui, Li, Yue-Qi, Yu, Lei, Yuan, Zi-Qing-Yun, Meng, Ling, Zhang, Hong-Wen, Wang, Yong-Qing
• Format: Journal Article
• Language: English
• Published: Cheshire Springer Healthcare 01.05.2017
• Subjects: Cardiology; Endocrinology; Esophagitis - drug therapy; Gastroesophageal Reflux - drug therapy; Health technology assessment; Helicobacter Infections - drug therapy; Humans; Internal Medicine; Medicine; Medicine & Public Health; Oncology; Peptic Ulcer - chemically induced; Pharmacology/Toxicology; Proton Pump Inhibitors - adverse effects; Proton Pump Inhibitors - pharmacology; Proton Pump Inhibitors - therapeutic use; Review; Rheumatology; infection; Peptic ulcer disease; Gastroesophageal reflux disease; Gastroenterology; Erosive esophagitis; Proton pump inhibitors; Adverse effects; Gastric acid-related diseases; Helicobacter pylori infection

Proton pump inhibitors (PPIs) are known as a class of pharmaceutical agents that target H + /K + -ATPase, which is located in gastric parietal cells. PPIs are widely used in the treatment of gastric acid-related diseases including peptic ulcer disease, erosive esophagitis and gastroesophageal reflux...