Synaptic stability and plasticity in a floating world

• Published in: Current opinion in neurobiology Vol. 20; no. 5; pp. 631 - 639
• Main Authors: Gerrow, Kimberly, Triller, Antoine
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.10.2010
• Subjects: Animals; Data processing; Humans; Membrane Proteins - chemistry; Membrane Proteins - metabolism; Membrane Proteins - physiology; Neurobiology - methods; Neurology; Neuronal Plasticity - genetics; Neuronal Plasticity - physiology; Psychiatry; Receptors, Neurotransmitter - chemistry; Receptors, Neurotransmitter - metabolism; Receptors, Neurotransmitter - physiology; Synaptic Membranes - chemistry; Synaptic Membranes - metabolism; Synaptic Membranes - physiology

A fundamental feature of membranes is the lateral diffusion of lipids and proteins. Control of lateral diffusion provides a mechanism for regulating the structure and function of synapses. Single-particle tracking (SPT) has emerged as a powerful way to directly visualize these movements. SPT can rev...