MiR-492 contributes to cell proliferation and cell cycle of human breast cancer cells by suppressing SOX7 expression

• Published in: Tumor biology Vol. 36; no. 3; pp. 1913 - 1921
• Main Authors: Shen, Fei, Cai, Wen-Song, Feng, Zhe, Li, Jiang-Lin, Chen, Ji-Wei, Cao, Jie, Xu, Bo
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer Netherlands 01.03.2015; Springer Nature B.V
• Subjects: 3' Untranslated Regions; Biomedical and Life Sciences; Biomedicine; Breast cancer; Breast Neoplasms - genetics; Breast Neoplasms - metabolism; Breast Neoplasms - pathology; Cancer Research; Cell cycle; Cell Cycle - physiology; Cell Division - genetics; Cell growth; Cell Line, Tumor; Cell Proliferation - physiology; Down-Regulation; Female; Gene expression; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; MCF-7 Cells; MicroRNAs; MicroRNAs - genetics; MicroRNAs - metabolism; Research Article; SOXF Transcription Factors - biosynthesis; SOXF Transcription Factors - genetics; Tumorigenesis; Up-Regulation; Cell proliferation; Breast cancer; MiR-492; SOX7; Cell cycle

MicroRNAs (miRNAs) have emerged as important regulators that potentially play critical roles in cancer cell biological processes. Previous studies have shown that miR-492 plays an important role in cell tumorigenesis in multiple kinds of human cancer cells. However, the underlying mechanisms of this...