Prognostic impact of early nutritional support in patients affected by locally advanced and metastatic pancreatic ductal adenocarcinoma undergoing chemotherapy

• Published in: European journal of clinical nutrition Vol. 72; no. 5; pp. 772 - 779
• Main Authors: Trestini, Ilaria, Carbognin, Luisa, Sperduti, Isabella, Bonaiuto, Clelia, Auriemma, Alessandra, Melisi, Davide, Salvatore, Lisa, Bria, Emilio, Tortora, Giampaolo
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.05.2018; Nature Publishing Group
• Subjects: 631/67/1504/1713; 692/308; Adenocarcinoma; Adult; Aged; Aged, 80 and over; Body Mass Index; Body size; Body weight gain; Body weight loss; Cancer patients; Carcinoma, Pancreatic Ductal - complications; Carcinoma, Pancreatic Ductal - therapy; Care and treatment; Chemotherapy; Clinical Nutrition; Counseling; Diagnosis; Diet; Early Diagnosis; Endpoint Determination; Energy intake; Epidemiology; Female; Follow-Up Studies; Food and nutrition; Health aspects; Humans; Internal Medicine; Male; Malnutrition; Malnutrition - diagnosis; Malnutrition - etiology; Malnutrition - therapy; Medical prognosis; Medicine; Medicine & Public Health; Metabolic Diseases; Metastases; Metastasis; Middle Aged; Multivariate analysis; Neoplasm Metastasis; Nutrition; Nutrition Assessment; Nutritional Status; Nutritional Support; Pancreas; Pancreatic cancer; Patients; Prevention; Prognosis; Proportional Hazards Models; Public Health; Retrospective Studies; Risk Factors; Surgery; Treatment Outcome; Weight Gain; Weight Loss

Background/objectives The aim of this analysis was to determine the risk of malnutrition and the prognostic value of nutritional intervention in patients affected by pancreatic ductal adenocarcinoma (PDAC) undergoing chemotherapy. Subjects/methods Clinical–pathological and nutritional data were corr...