Disproportionate cardiac hypertrophy during early postnatal development in infants born preterm

• Published in: Pediatric research Vol. 82; no. 1; pp. 36 - 46
• Main Authors: Aye, Christina Y L, Lewandowski, Adam J, Lamata, Pablo, Upton, Ross, Davis, Esther, Ohuma, Eric O, Kenworthy, Yvonne, Boardman, Henry, Wopperer, Samuel, Packham, Alice, Adwani, Satish, McCormick, Kenny, Papageorghiou, Aris T, Leeson, Paul
• Format: Journal Article
• Language: English
• Published: New York Nature Publishing Group US 01.07.2017; Nature Publishing Group
• Subjects: 692/4019/592/75/74/1540; 692/700/1720/3185; 692/700/1720/3187; Age; Anthropometry; Birth Weight; Blood Pressure; Body Size; Cardiomegaly - diagnostic imaging; Cardiomegaly - physiopathology; Cardiovascular disease; clinical-investigation; Computer Simulation; Echocardiography; Female; Gestational Age; Heart - diagnostic imaging; Heart - growth & development; Heart Ventricles - diagnostic imaging; Heart Ventricles - growth & development; Humans; Infant; Infant, Newborn; Infant, Premature; Male; Medicine; Medicine & Public Health; Pediatric Surgery; Pediatrics; Premature birth; Time Factors; Ultrasonography; Ventricular Function, Right

Background Adults born very preterm have increased cardiac mass and reduced function. We investigated whether a hypertrophic phenomenon occurs in later preterm infants and when this occurs during early development. Methods Cardiac ultrasound was performed on 392 infants (33% preterm at mean gestatio...