Effect of systemic inflammatory response on induction chemotherapy followed by chemoradiotherapy for locally advanced pancreatic cancer: an exploratory subgroup analysis on systemic inflammatory response in JCOG1106

• Published in: Japanese journal of clinical oncology Vol. 53; no. 8; pp. 704 - 713
• Main Authors: Mizuno, Nobumasa, Ioka, Tatsuya, Ogawa, Gakuto, Nakamura, Satoaki, Hiraoka, Nobuyoshi, Ito, Yoshinori, Katayama, Hiroshi, Takada, Ryoji, Kobayashi, Satoshi, Ikeda, Masafumi, Miwa, Haruo, Okano, Naohiro, Kuramochi, Hidekazu, Sekimoto, Mitsugu, Okusaka, Takuji, Ozaka, Masato, Todaka, Akiko, Gotoh, Kunihito, Tobimatsu, Kazutoshi, Yamaguchi, Hironori, Nakagohri, Toshio, Kajiura, Shinya, Sudo, Kentaro, Okamura, Keiya, Shimizu, Satoshi, Shirakawa, Hirofumi, Kato, Naoya, Sano, Keiji, Iwai, Tomohisa, Fujimori, Nao, Ueno, Makoto, Ishii, Hiroshi, Furuse, Junji
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 31.07.2023
• Subjects: Original; Glasgow prognostic score; gemcitabine; treatment interaction; S-1 concurrent radiotherapy

Abstract Objective JCOG1106, a randomized phase II trial conducted to compare chemoradiotherapy (S-1 concurrent radiotherapy) with (Arm B) or without (Arm A) induction chemotherapy using gemcitabine in patients with locally advanced pancreatic cancer, showed a more favorable long-term survival in Ar...