Anticancer activity of subfractions containing pure compounds of Chaga mushroom (Inonotus obliquus) extract in human cancer cells and in Balbc/c mice bearing Sarcoma-180 cells

• Published in: Nutrition research and practice Vol. 4; no. 3; pp. 177 - 182
• Main Authors: Chung, M.J., Kangwon National University, Chuncheon, Republic of Korea, Chung, C.K., Hallym University, Chuncheon, Republic of Korea, Jeong, Y.H., Dankook University, Yongin, Republic of Korea, Ham, S.S., Kangwon National University, Chuncheon, Republic of Korea
• Format: Journal Article
• Language: English
• Published: Korea (South) 한국영양학회 01.06.2010; The Korean Nutrition Society and the Korean Society of Community Nutrition
• Subjects: Antitumor; cancer cells; CHAMPIGNON COMESTIBLE; EDIBLE FUNGI; Inonotus obliquus; mouse tumor; NEOPLASMAS; NEOPLASME; NEOPLASMS; Original; SETAS COMESTIBLES; 생활과학; cancer; cancer cells; mouse tumor; mushroom; Antitumor

The Chaga mushroom (Inonotus obliquus) has been used in folk medicine to treat cancers. However, limited information exists on the underlying anticancer effects of the major component of I. obliquus in vivo. We hypothesize that the pure compounds (3β-hydroxy-lanosta-8,24-dien-21-al, inotodiol and la...