A phylogenetic and proteomic reconstruction of eukaryotic chromatin evolution

• Published in: Nature ecology & evolution Vol. 6; no. 7; pp. 1007 - 1023
• Main Authors: Grau-Bové, Xavier, Navarrete, Cristina, Chiva, Cristina, Pribasnig, Thomas, Antó, Meritxell, Torruella, Guifré, Galindo, Luis Javier, Lang, Bernd Franz, Moreira, David, López-Garcia, Purificación, Ruiz-Trillo, Iñaki, Schleper, Christa, Sabidó, Eduard, Sebé-Pedrós, Arnau
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.07.2022; Nature Publishing Group; Nature
• Subjects: 631/114; 631/181; 631/208/176; 631/208/212/748; 631/326/26; 82/58; Archaea; Biological and Physical Anthropology; Biomedical and Life Sciences; Chromatin; Ecology; Eukaryotes; Evolution; Evolutionary Biology; Evolutionary genetics; Genomics; Histones; Life Sciences; Paleontology; Parasites; Phylogenetics; Phylogeny; Post-translation; Proteomics; Zoology

Histones and associated chromatin proteins have essential functions in eukaryotic genome organization and regulation. Despite this fundamental role in eukaryotic cell biology, we lack a phylogenetically comprehensive understanding of chromatin evolution. Here, we combine comparative proteomics and g...