Attenuated cardiovascular reserve during prolonged submaximal cycle exercise in healthy older subjects

• Published in: Journal of the American College of Cardiology Vol. 40; no. 7; pp. 1290 - 1297
• Main Authors: Correia, Luis C.L, Lakatta, Edward G, O’Connor, Frances C, Becker, Lewis C, Clulow, Jon, Townsend, Susan, Gerstenblith, Gary, Fleg, Jerome L
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 02.10.2002; Elsevier Science; Elsevier Limited
• Subjects: Adult; Age; Age Factors; Aged; Aged, 80 and over; Aging - physiology; Biological and medical sciences; Blood pressure; Cameras; Cardiac Volume - physiology; Cardiology; Cardiovascular system; Exercise; Exercise Test - methods; Female; Fitness equipment; Heart rate; Heart Rate - physiology; Hemodynamics - physiology; Humans; Investigative techniques of hemodynamics; Investigative techniques, diagnostic techniques (general aspects); Male; Medical sciences; Middle Aged; Oxygen Consumption - physiology; Radionuclide Ventriculography; Reference Values; Stroke Volume - physiology; Time Factors; Ventricular Function, Left - physiology; a-vO2; SBP; EF; ESVI; PSE; SV; CI; BLSA; SVI; ESV; HR; LV; EAI; BP; EDVI; DBP; CNTR; EDV; VO2; VO2max; MBP; TSVR; Human; Physical exercise; Exploration; Circulatory system; Hemodynamics; Left ventricle performance; Elderly

The goal of this study was to determine the effect of age on the hemodynamic response to prolonged submaximal aerobic exercise in healthy volunteers. Reductions in peak work rate, heart rate (HR), and left ventricular (LV) emptying but higher blood pressure (BP) and systemic vascular resistance occu...