Osseointegration potential of boron-coated titanium alloy pedicle screw in rabbit spine model

• Published in: BMC musculoskeletal disorders Vol. 25; no. 1; pp. 737 - 8
• Main Authors: Ozer, Hidir, Hekimoğlu, Mehdi, Kulac, Ibrahim, Eren, Ozgur Can, Arici, Yeliz Kasko, Çelik, Haydar, Ozer, Ali Fahir
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 14.09.2024; BioMed Central; BMC
• Subjects: Alloys; Anesthesia; Animal models; Animals; Back surgery; Biomechanics; Bone implants; Bone marrow; Boron; Boron - chemistry; Boron - pharmacology; Boronization; Coated Materials, Biocompatible; Coatings; Decalcification; Fibrosis; Histology; Instrumantatin failure; Lumbar Vertebrae - surgery; Male; Materials; Mechanical properties; Morphology; Necrosis; Osseointegratıon; Osseointegration; Osseointegration - drug effects; Pedicle Screws; Properties; Rabbits; Specialty metals industry; Spine; Spine (lumbar); Spine surgery; Statistical analysis; Stem cells; Surgery; Titanium; Titanium alloys; Titanyum alloy; Transplants & implants; Vascularization; Vertebrae; Turkey; Boronization; Instrumantatin failure; Osseointegratıon; Spine surgery; Titanyum alloy

Spinal implants' longevity is crucial, but titanium alloys, while advantageous, lack strong bone integration. This study aimed to achieve better osseointegration rates by utilizing the ability of boron compounds to transform stem cells in the vertebra into osteoblasts. Twenty male albino rabbit...