Developmental expression patterns of cuticular protein genes with the R&R Consensus from Anopheles gambiae

• Published in: Insect biochemistry and molecular biology Vol. 38; no. 5; pp. 508 - 519
• Main Authors: Togawa, Toru, Dunn, W. Augustine, Emmons, Aaron C., Nagao, John, Willis, Judith H.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.05.2008
• Subjects: Animals; Anopheles - genetics; Anopheles - growth & development; Anopheles - metabolism; Anopheles gambiae; Arthropoda; Consensus Sequence; CPR; Cuticle; Cuticular protein; developmental stages; females; Gene cluster; gene dosage; Gene dosage compensation; Gene Expression; gene expression regulation; Gene Expression Regulation, Developmental; genome; insect cuticle; insect development; insect proteins; Insect Proteins - chemistry; Insect Proteins - genetics; Insect Proteins - metabolism; linkage (genetics); males; molecular sequence data; molting; Multigene Family; nucleotide sequences; protein synthesis; R&R Consensus; Real-time qRT-PCR; Reverse Transcriptase Polymerase Chain Reaction; Sex Characteristics; sex linkage; temporal variation; Gene cluster; CPR; Cuticular protein; Cuticle; R&R Consensus; Real-time qRT-PCR; Gene dosage compensation

CPR proteins are the largest cuticular protein family in arthropods. The whole genome sequence of Anopheles gambiae revealed 156 genes that code for proteins with the R&R Consensus and named CPRs. This protein family can be divided into RR-1 and RR-2 subgroups, postulated to contribute to differ...