Metaphor: Finding Bi-directional Best Hit homology relationships in (meta)genomic datasets

• Published in: Genomics (San Diego, Calif.) Vol. 104; no. 6; pp. 459 - 463
• Main Authors: van der Veen, Bernd E., Harris, Hugh M., O´Toole, Paul W., Claesson, Marcus J.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.12.2014
• Subjects: Bi-directional Best Hit; BLAST; Genomics; homology; Lactobacillus - genetics; Metagenome; Metagenomics; Phylogeny; Sequence Alignment - methods; Sequence Analysis, DNA - methods; Software; Metagenomics; Bi-directional Best Hit; homology; BLAST; Genomics

As the number of assembled genome and metagenome sequences continue to grow at an ever-increasing pace, so does the need for fast, flexible and automated pipelines for generating meaningful homologous relationships within and between these (meta)genomes. Such relationships, or lack thereof, are cruc...