A Polyamidoamine Dendrimer-Based Electrochemical Immunosensor for Label-Free Determination of Epithelial Cell Adhesion Molecule- Expressing Cancer Cells

• Published in: Sensors (Basel, Switzerland) Vol. 19; no. 8; p. 1879
• Main Authors: Xu, Jianguo, Wang, Xinxin, Yan, Chao, Chen, Wei
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI 19.04.2019; MDPI AG
• Subjects: epithelial cell adhesion molecule (EpCAM), electrochemical impedance spectroscopy (EIS); immunosensor; label-free; polyamidoamine dendrimer; immunosensor; polyamidoamine dendrimer; label-free; epithelial cell adhesion molecule (EpCAM), electrochemical impedance spectroscopy (EIS)

A new electrochemical immunosensor for cancer cell detection based on a specific interaction between the metastasis-related antigen of epithelial cell adhesion molecule (EpCAM) on the cell membrane and its monoclonal antibody (Anti-EpCAM) immobilized on a gold electrode has been developed. The amino...