Histoplasma capsulatum urinary antigen detection in a kidney transplant recipient with acute paracoccidioidomycosis: Case study and literature review

• Published in: PLoS neglected tropical diseases Vol. 18; no. 8; p. e0012472
• Main Authors: Oliveira Bastos, Matheus, Varon, Andréa Gina, Theodoro, Pedro Henrique Nascimento, Falcão, Eduardo Mastrangelo Marinho, Zancopé-Oliveira, Rosely Maria, do Valle, Antonio Carlos Francesconi, Almeida-Paes, Rodrigo, de Macedo, Priscila Marques
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 29.08.2024
• Subjects: Acute Disease; Analysis; Antigens, Fungal - immunology; Antigens, Fungal - urine; Biology and Life Sciences; Case studies; Cross Reactions; Diagnosis; False Positive Reactions; Galactose - analogs & derivatives; Histoplasma - immunology; Histoplasma capsulatum; Histoplasmosis; Histoplasmosis - complications; Histoplasmosis - immunology; Histoplasmosis - microbiology; Histoplasmosis - urine; Humans; Immunocompromised Host; Kidney Transplantation; Kidneys; Mannans - urine; Medicine and Health Sciences; Organ transplant recipients; Paracoccidioidomycosis; Paracoccidioidomycosis - complications; Paracoccidioidomycosis - diagnosis; Paracoccidioidomycosis - urine; Research and Analysis Methods; Transplant Recipients; Transplantation; Urine; Brazil

Paracoccidioidomycosis (PCM) and histoplasmosis are endemic fungal diseases in South America. Both can lead to lung involvement with fungal dissemination progressing to systemic and severe clinical manifestations, especially in immunosuppressed hosts. As the population of immunosuppressed individual...