Histoplasma capsulatum urinary antigen detection in a kidney transplant recipient with acute paracoccidioidomycosis: Case study and literature review

Paracoccidioidomycosis (PCM) and histoplasmosis are endemic fungal diseases in South America. Both can lead to lung involvement with fungal dissemination progressing to systemic and severe clinical manifestations, especially in immunosuppressed hosts. As the population of immunosuppressed individual...

Full description

Saved in:
Bibliographic Details
Published inPLoS neglected tropical diseases Vol. 18; no. 8; p. e0012472
Main Authors Oliveira Bastos, Matheus, Varon, Andréa Gina, Theodoro, Pedro Henrique Nascimento, Falcão, Eduardo Mastrangelo Marinho, Zancopé-Oliveira, Rosely Maria, do Valle, Antonio Carlos Francesconi, Almeida-Paes, Rodrigo, de Macedo, Priscila Marques
Format Journal Article
LanguageEnglish
Published United States Public Library of Science 29.08.2024
Subjects
Acute Disease
Analysis
Antigens, Fungal - immunology
Antigens, Fungal - urine
Biology and Life Sciences
Case studies
Cross Reactions
Diagnosis
False Positive Reactions
Galactose - analogs & derivatives
Histoplasma - immunology
Histoplasma capsulatum
Histoplasmosis
Histoplasmosis - complications
Histoplasmosis - immunology
Histoplasmosis - microbiology
Histoplasmosis - urine
Humans
Immunocompromised Host
Kidney Transplantation
Kidneys
Mannans - urine
Medicine and Health Sciences
Organ transplant recipients
Paracoccidioidomycosis
Paracoccidioidomycosis - complications
Paracoccidioidomycosis - diagnosis
Paracoccidioidomycosis - urine
Research and Analysis Methods
Transplant Recipients
Transplantation
Urine
Brazil
Online AccessGet full text

Cover

Abstract Paracoccidioidomycosis (PCM) and histoplasmosis are endemic fungal diseases in South America. Both can lead to lung involvement with fungal dissemination progressing to systemic and severe clinical manifestations, especially in immunosuppressed hosts. As the population of immunosuppressed individuals has been rising, a higher occurrence of fungal infections is predicted in this setting. This poses challenges regarding the differential diagnosis due to overlapping clinical and laboratorial findings, hampering the management of cases. In this study, the authors discuss the occurrence of a false-positive Histoplasma urinary antigen detection in a kidney transplant recipient with acute PCM. Given the scarce information about this subject, a review on literature data is provided. A comprehensive literature search was conducted to investigate previous studies that found cross-reactivity between Histoplasma urinary antigen assays in human patients with confirmed diagnosis of PCM. Additionally, an update of PCM in transplant recipients is provided. The included studies reported 120 samples from patients with PCM tested for Histoplasma antigen, presenting an overall cross-reactivity of 51.67% and 17 cases of PCM in transplant recipients. CONCLUSIONS: The galactomannan urinary antigen developed to diagnose histoplasmosis can cross react with PCM, which may represent a concern in countries where both mycoses overlap.
AbstractList Paracoccidioidomycosis (PCM) and histoplasmosis are endemic fungal diseases in South America. Both can lead to lung involvement with fungal dissemination progressing to systemic and severe clinical manifestations, especially in immunosuppressed hosts. As the population of immunosuppressed individuals has been rising, a higher occurrence of fungal infections is predicted in this setting. This poses challenges regarding the differential diagnosis due to overlapping clinical and laboratorial findings, hampering the management of cases. In this study, the authors discuss the occurrence of a false-positive Histoplasma urinary antigen detection in a kidney transplant recipient with acute PCM. Given the scarce information about this subject, a review on literature data is provided. A comprehensive literature search was conducted to investigate previous studies that found cross-reactivity between Histoplasma urinary antigen assays in human patients with confirmed diagnosis of PCM. Additionally, an update of PCM in transplant recipients is provided. The included studies reported 120 samples from patients with PCM tested for Histoplasma antigen, presenting an overall cross-reactivity of 51.67% and 17 cases of PCM in transplant recipients. CONCLUSIONS: The galactomannan urinary antigen developed to diagnose histoplasmosis can cross react with PCM, which may represent a concern in countries where both mycoses overlap.
Paracoccidioidomycosis (PCM) and histoplasmosis are endemic fungal diseases in South America. Both can lead to lung involvement with fungal dissemination progressing to systemic and severe clinical manifestations, especially in immunosuppressed hosts. As the population of immunosuppressed individuals has been rising, a higher occurrence of fungal infections is predicted in this setting. This poses challenges regarding the differential diagnosis due to overlapping clinical and laboratorial findings, hampering the management of cases.BACKGROUNDParacoccidioidomycosis (PCM) and histoplasmosis are endemic fungal diseases in South America. Both can lead to lung involvement with fungal dissemination progressing to systemic and severe clinical manifestations, especially in immunosuppressed hosts. As the population of immunosuppressed individuals has been rising, a higher occurrence of fungal infections is predicted in this setting. This poses challenges regarding the differential diagnosis due to overlapping clinical and laboratorial findings, hampering the management of cases.In this study, the authors discuss the occurrence of a false-positive Histoplasma urinary antigen detection in a kidney transplant recipient with acute PCM. Given the scarce information about this subject, a review on literature data is provided.OBJECTIVESIn this study, the authors discuss the occurrence of a false-positive Histoplasma urinary antigen detection in a kidney transplant recipient with acute PCM. Given the scarce information about this subject, a review on literature data is provided.A comprehensive literature search was conducted to investigate previous studies that found cross-reactivity between Histoplasma urinary antigen assays in human patients with confirmed diagnosis of PCM. Additionally, an update of PCM in transplant recipients is provided.METHODSA comprehensive literature search was conducted to investigate previous studies that found cross-reactivity between Histoplasma urinary antigen assays in human patients with confirmed diagnosis of PCM. Additionally, an update of PCM in transplant recipients is provided.The included studies reported 120 samples from patients with PCM tested for Histoplasma antigen, presenting an overall cross-reactivity of 51.67% and 17 cases of PCM in transplant recipients. CONCLUSIONS: The galactomannan urinary antigen developed to diagnose histoplasmosis can cross react with PCM, which may represent a concern in countries where both mycoses overlap.FINDINGSThe included studies reported 120 samples from patients with PCM tested for Histoplasma antigen, presenting an overall cross-reactivity of 51.67% and 17 cases of PCM in transplant recipients. CONCLUSIONS: The galactomannan urinary antigen developed to diagnose histoplasmosis can cross react with PCM, which may represent a concern in countries where both mycoses overlap.
Paracoccidioidomycosis (PCM) and histoplasmosis are severe fungal diseases occurring simultaneously in South America. They can cause similar clinical manifestations, especially in immunosuppressed hosts. This poses challenges regarding the differential diagnosis due to overlapping clinical and laboratorial findings, hampering the management of individual cases. In this study, the authors report the occurrence of a false-positive urinary test to detect histoplasmosis in a kidney transplant recipient with acute PCM. Given the scarce information about this subject, a review on literature data is provided. As conclusion, this study highlights the urinary test developed to diagnose histoplasmosis can cross react with PCM, which may represent a concern in countries where both mycoses overlap.
Background Paracoccidioidomycosis (PCM) and histoplasmosis are endemic fungal diseases in South America. Both can lead to lung involvement with fungal dissemination progressing to systemic and severe clinical manifestations, especially in immunosuppressed hosts. As the population of immunosuppressed individuals has been rising, a higher occurrence of fungal infections is predicted in this setting. This poses challenges regarding the differential diagnosis due to overlapping clinical and laboratorial findings, hampering the management of cases. Objectives In this study, the authors discuss the occurrence of a false-positive Histoplasma urinary antigen detection in a kidney transplant recipient with acute PCM. Given the scarce information about this subject, a review on literature data is provided. Methods A comprehensive literature search was conducted to investigate previous studies that found cross-reactivity between Histoplasma urinary antigen assays in human patients with confirmed diagnosis of PCM. Additionally, an update of PCM in transplant recipients is provided. Findings The included studies reported 120 samples from patients with PCM tested for Histoplasma antigen, presenting an overall cross-reactivity of 51.67% and 17 cases of PCM in transplant recipients. CONCLUSIONS: The galactomannan urinary antigen developed to diagnose histoplasmosis can cross react with PCM, which may represent a concern in countries where both mycoses overlap.
Paracoccidioidomycosis (PCM) and histoplasmosis are endemic fungal diseases in South America. Both can lead to lung involvement with fungal dissemination progressing to systemic and severe clinical manifestations, especially in immunosuppressed hosts. As the population of immunosuppressed individuals has been rising, a higher occurrence of fungal infections is predicted in this setting. This poses challenges regarding the differential diagnosis due to overlapping clinical and laboratorial findings, hampering the management of cases. In this study, the authors discuss the occurrence of a false-positive Histoplasma urinary antigen detection in a kidney transplant recipient with acute PCM. Given the scarce information about this subject, a review on literature data is provided. A comprehensive literature search was conducted to investigate previous studies that found cross-reactivity between Histoplasma urinary antigen assays in human patients with confirmed diagnosis of PCM. Additionally, an update of PCM in transplant recipients is provided. The included studies reported 120 samples from patients with PCM tested for Histoplasma antigen, presenting an overall cross-reactivity of 51.67% and 17 cases of PCM in transplant recipients. CONCLUSIONS: The galactomannan urinary antigen developed to diagnose histoplasmosis can cross react with PCM, which may represent a concern in countries where both mycoses overlap.
Audience Academic
Author de Macedo, Priscila Marques
Theodoro, Pedro Henrique Nascimento
Zancopé-Oliveira, Rosely Maria
Almeida-Paes, Rodrigo
Falcão, Eduardo Mastrangelo Marinho
Oliveira Bastos, Matheus
Varon, Andréa Gina
do Valle, Antonio Carlos Francesconi
AuthorAffiliation 3 Laboratório de Micologia, Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Brazil
Albert Einstein College of Medicine, UNITED STATES OF AMERICA
1 Serviço de Atenção de Pacientes Internados, Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Brazil
2 Laboratório de Pesquisa Clínica em Dermatologia Infecciosa, Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Brazil
AuthorAffiliation_xml – name: Albert Einstein College of Medicine, UNITED STATES OF AMERICA
– name: 1 Serviço de Atenção de Pacientes Internados, Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Brazil
– name: 2 Laboratório de Pesquisa Clínica em Dermatologia Infecciosa, Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Brazil
– name: 3 Laboratório de Micologia, Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Brazil
Author_xml – sequence: 1
  givenname: Matheus
  surname: Oliveira Bastos
  fullname: Oliveira Bastos, Matheus
– sequence: 2
  givenname: Andréa Gina
  surname: Varon
  fullname: Varon, Andréa Gina
– sequence: 3
  givenname: Pedro Henrique Nascimento
  surname: Theodoro
  fullname: Theodoro, Pedro Henrique Nascimento
– sequence: 4
  givenname: Eduardo Mastrangelo Marinho
  surname: Falcão
  fullname: Falcão, Eduardo Mastrangelo Marinho
– sequence: 5
  givenname: Rosely Maria
  surname: Zancopé-Oliveira
  fullname: Zancopé-Oliveira, Rosely Maria
– sequence: 6
  givenname: Antonio Carlos Francesconi
  surname: do Valle
  fullname: do Valle, Antonio Carlos Francesconi
– sequence: 7
  givenname: Rodrigo
  surname: Almeida-Paes
  fullname: Almeida-Paes, Rodrigo
– sequence: 8
  givenname: Priscila Marques
  orcidid: 0000-0002-6900-9703
  surname: de Macedo
  fullname: de Macedo, Priscila Marques
BackLink https://www.ncbi.nlm.nih.gov/pubmed/39208382$$D View this record in MEDLINE/PubMed
BookMark eNp9kt-K1DAUxousuH_0DUQCgngzY9K002ZvlmVQV1jwRq9DmpzOnDVNapLusg_i-5oy4zIjIrloaH7fd85JvvPixHkHRfGa0SXjDftw56fglF2OLpklpaysmvJZccYErxdlw-uTg_1pcR7jHaW1qFv2ojjloqQtb8uz4tcNxuRHq-KgiFZjnKxK00CmgE6FR6Jcwg04YiCBTugdQUcU-YHGwSNJQbmYxS6RABpHhLx7wLQlSk8JyKiC0l5rNOjR-OFR-4jxkqxVBBLTZOYChlhMEHLZANnmHuHhZfG8VzbCq_33ovj-6eO39c3i9uvnL-vr24WuaZMWsGq5VrzlatVUohGsqw2lmmrOa1Z1Je27novKiKqt-66mtGRg9CovqnjX9_yiuNr5jlM35KPcflBWjgGHPLz0CuXxicOt3Ph7yRhvhSjb7PB-7xD8zwlikgNGDTbfCfgpSk5FbkzUqxl9u0M3yoJE1_tsqWdcXre0oStWNTxTy39QeRkYUOcI9Jj_HwneHQi2oGzaRm-n-bHiMfjmcNinKf-EIQPVDtDBxxigf0IYlXPm5D5zcs6c3Gcuyy7_kmlMai6fO0f7f_FvcPLlDQ
CitedBy_id crossref_primary_10_1093_mmy_myae125
Cites_doi 10.1086/513647
10.3390/jof3010001
10.1093/cid/cit593
10.1590/0037-8682-0282-2016
10.3390/jof8101098
10.1590/0037-8682-0110-2022
10.1016/j.transproceed.2015.03.006
10.1007/s11046-021-00602-9
10.1007/s12281-022-00441-1
10.1016/j.cll.2023.02.005
10.1080/02681219580000781
10.1111/j.1439-0507.2008.01687.x
10.3201/eid2311.170934
10.1007/BF01259396
10.1111/ctr.13553
10.3390/jof7010012
10.1128/jcm.35.10.2618-2622.1997
10.1128/CVI.00332-09
10.1007/BF02055979
10.1186/s12929-023-00926-2
10.3390/jof6040293
10.1016/j.mmcr.2021.02.004
10.3390/jof5010002
10.1128/CVI.00101-14
10.1590/S0036-46652004000500009
10.1128/aem.02010-21
10.1309/Q7879TYDW5D93QK7
10.1016/j.abd.2020.07.011
10.1086/318146
10.1080/14737159.2023.2267977
10.1093/cid/cir435
10.1128/JCM.38.8.2909-2913.2000
10.2174/1568026618666181002112231
10.1111/tid.12655
10.3390/jof9090946
10.1371/journal.pntd.0011645
10.1371/journal.pntd.0003174
10.4269/ajtmh.18-1008
10.1016/j.transproceed.2008.02.049
10.1371/journal.pntd.0010529
10.3390/jof7100799
10.1128/jcm.35.9.2252-2255.1997
10.1128/CVI.00066-09
10.1016/S1473-3099(21)00191-2
10.1128/CVI.00071-07
10.1007/s12281-011-0081-7
10.1590/0037-8682-0230-2017
10.1128/JCM.01959-17
ContentType Journal Article
Copyright Copyright: © 2024 Oliveira Bastos et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
COPYRIGHT 2024 Public Library of Science
2024 Oliveira Bastos et al 2024 Oliveira Bastos et al
Copyright_xml – notice: Copyright: © 2024 Oliveira Bastos et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
– notice: COPYRIGHT 2024 Public Library of Science
– notice: 2024 Oliveira Bastos et al 2024 Oliveira Bastos et al
DBID AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
7X8
5PM
DOI 10.1371/journal.pntd.0012472
DatabaseName CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
MEDLINE - Academic
PubMed Central (Full Participant titles)
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
MEDLINE - Academic
DatabaseTitleList MEDLINE
MEDLINE - Academic
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
DocumentTitleAlternate Histoplasma urinary antigen detection in transplant recipient with paracoccidioidomycosis
EISSN 1935-2735
ExternalDocumentID PMC11389928
A807061473
39208382
10_1371_journal_pntd_0012472
Genre Journal Article
Review
Case Reports
GeographicLocations Brazil
GeographicLocations_xml – name: Brazil
GrantInformation_xml – fundername: ;
– fundername: ;
  grantid: E-26/200.381/2023
– fundername: ;
  grantid: 308315/2021-9 and 316067/2021-0
– fundername: ;
  grantid: FAPERJ E-26/211.430/2021
GroupedDBID ---
123
29O
2WC
53G
5VS
7X7
88E
8C1
8FI
8FJ
AAFWJ
AAUCC
AAWOE
AAYXX
ABDBF
ABUWG
ACGFO
ACIHN
ACPRK
ACUHS
ADBBV
AEAQA
AENEX
AEUYN
AFKRA
AFPKN
AFRAH
AHMBA
ALIPV
ALMA_UNASSIGNED_HOLDINGS
AOIJS
BAWUL
BCNDV
BENPR
BPHCQ
BVXVI
BWKFM
CCPQU
CITATION
CS3
DIK
DU5
E3Z
EAP
EAS
EBD
ECGQY
EMOBN
ESX
F5P
FPL
FYUFA
GROUPED_DOAJ
GX1
HMCUK
HYE
IAO
IHR
IHW
ITC
KQ8
M1P
M48
O5R
O5S
OK1
OVT
P2P
PGMZT
PHGZM
PHGZT
PIMPY
PQQKQ
PROAC
PSQYO
PV9
RNS
RPM
RZL
SV3
TR2
TUS
UKHRP
3V.
ADRAZ
CGR
CUY
CVF
ECM
EIF
H13
IPNFZ
M~E
NPM
RIG
WOQ
PMFND
7X8
PPXIY
5PM
PJZUB
ID FETCH-LOGICAL-c507t-e683ca383a6749791b5d00c0c33514b20fbf394d9485fb50021edc6c6c0a3bff3
IEDL.DBID M48
ISSN 1935-2735
1935-2727
IngestDate Thu Aug 21 18:35:19 EDT 2025
Fri Jul 11 04:24:31 EDT 2025
Tue Jun 17 22:04:14 EDT 2025
Tue Jun 10 21:02:02 EDT 2025
Thu May 22 21:24:07 EDT 2025
Wed Jan 29 09:33:18 EST 2025
Thu Apr 24 23:04:12 EDT 2025
Tue Jul 01 01:43:31 EDT 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 8
Language English
License Copyright: © 2024 Oliveira Bastos et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c507t-e683ca383a6749791b5d00c0c33514b20fbf394d9485fb50021edc6c6c0a3bff3
Notes new_version
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Review-3
content type line 23
ObjectType-Case Study-5
ObjectType-Feature-2
ObjectType-Report-4
The authors have declared that no competing interests exist.
ORCID 0000-0002-6900-9703
OpenAccessLink http://journals.scholarsportal.info/openUrl.xqy?doi=10.1371/journal.pntd.0012472
PMID 39208382
PQID 3099799568
PQPubID 23479
ParticipantIDs pubmedcentral_primary_oai_pubmedcentral_nih_gov_11389928
proquest_miscellaneous_3099799568
gale_infotracmisc_A807061473
gale_infotracacademiconefile_A807061473
gale_healthsolutions_A807061473
pubmed_primary_39208382
crossref_primary_10_1371_journal_pntd_0012472
crossref_citationtrail_10_1371_journal_pntd_0012472
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 20240829
PublicationDateYYYYMMDD 2024-08-29
PublicationDate_xml – month: 8
  year: 2024
  text: 20240829
  day: 29
PublicationDecade 2020
PublicationPlace United States
PublicationPlace_xml – name: United States
– name: San Francisco, CA USA
PublicationTitle PLoS neglected tropical diseases
PublicationTitleAlternate PLoS Negl Trop Dis
PublicationYear 2024
Publisher Public Library of Science
Publisher_xml – name: Public Library of Science
References PM Peçanha (pntd.0012472.ref051) 2022; 8
I Azuma (pntd.0012472.ref057) 1974; 54
ML Taylor (pntd.0012472.ref002) 2022; 88
KA Linder (pntd.0012472.ref010) 2020; 7
E Marin (pntd.0012472.ref031) 2023; 83
CRA Felipe (pntd.0012472.ref044) 2021
G Benard (pntd.0012472.ref047) 2000; 31
DH Cáceres (pntd.0012472.ref028) 2021; 7
JL Saullo (pntd.0012472.ref005) 2022; 16
W Abdallah (pntd.0012472.ref029) 2021; 8
DA Enoch (pntd.0012472.ref008) 2017
CP Taborda (pntd.0012472.ref003) 2018; 18
PA Connolly (pntd.0012472.ref016) 2007; 14
R Miller (pntd.0012472.ref004) 2019; 33
M Assi (pntd.0012472.ref014) 2013; 57
GR Thompson (pntd.0012472.ref058) 2021; 21
JD Jenks (pntd.0012472.ref011) 2023; 23
MA Reis (pntd.0012472.ref040) 1995; 88
D Zacharias (pntd.0012472.ref056) 1986; 24
T Oni (pntd.0012472.ref046) 2015
CM Scheel (pntd.0012472.ref025) 2009; 16
DH Caceres (pntd.0012472.ref026) 2014; 21
J Sifuentes-Osornio (pntd.0012472.ref007) 2012; 6
EM Falcão (pntd.0012472.ref049) 2022; 16
RC Hahn (pntd.0012472.ref052) 2022; 35
J Batista (pntd.0012472.ref054) 2010; 53
AP Zavascki (pntd.0012472.ref034) 2004; 46
TC Lima (pntd.0012472.ref038) 2017; 50
BG Pinheiro (pntd.0012472.ref059) 2020; 6
AM Sugar (pntd.0012472.ref032) 1984; 129
ACF Do Valle (pntd.0012472.ref018) 2017; 23
MSM Vidal (pntd.0012472.ref053) 2014; 8
BL Gomez (pntd.0012472.ref023) 1997; 35
Jr. J De Almeida (pntd.0012472.ref006) 2018; 5
C Sinkos (pntd.0012472.ref042) 2021; 32
G San-Blas (pntd.0012472.ref055) 1977; 62
DH Cáceres (pntd.0012472.ref030) 2022; 187
JL Cloud (pntd.0012472.ref021) 2007; 128
S Campos (pntd.0012472.ref041) 2008; 40
W Fang (pntd.0012472.ref009) 2023; 30
FDO Valentim (pntd.0012472.ref043) 2021; 96
MV Radisic (pntd.0012472.ref037) 2017; 19
EMM Falcão (pntd.0012472.ref048) 2023; 9
MA Shikanai-Yasuda (pntd.0012472.ref001) 2017; 50
Durães SMB Góes HFDO (pntd.0012472.ref036) 2016; 58
FV Pereira (pntd.0012472.ref045) 2022; 55
R. Martinez (pntd.0012472.ref017) 2017; 3
LMP Benko (pntd.0012472.ref050) 2023; 17
Brito ESD Soares LSDS (pntd.0012472.ref019) 2020
CA Hage (pntd.0012472.ref013) 2011; 53
TO Garringer (pntd.0012472.ref022) 2000; 38
PM Peçanha-Pietrobom (pntd.0012472.ref039) 2019; 101
C Muñoz (pntd.0012472.ref020) 2010; 17
J Wheat (pntd.0012472.ref015) 1997; 24
MM Durkin (pntd.0012472.ref024) 1997; 35
PM Luethy (pntd.0012472.ref012) 2023; 43
AM Pontes (pntd.0012472.ref035) 2015; 47
DH Cáceres (pntd.0012472.ref027) 2018; 56
MA Shikanai-Yasuda (pntd.0012472.ref033) 1995; 33
References_xml – volume: 24
  start-page: 1169
  year: 1997
  ident: pntd.0012472.ref015
  article-title: Cross-Reactivity in Histoplasma capsulatum variety capsulatum Antigen Assays of Urine Samples from Patients with Endemic Mycoses
  publication-title: Clin Infect Dis
  doi: 10.1086/513647
– volume: 3
  start-page: 1
  year: 2017
  ident: pntd.0012472.ref017
  article-title: New Trends in Paracoccidioidomycosis Epidemiology.
  publication-title: J Fungi.
  doi: 10.3390/jof3010001
– volume: 57
  start-page: 1542
  year: 2013
  ident: pntd.0012472.ref014
  article-title: Histoplasmosis After Solid Organ Transplant
  publication-title: Clin Infect Dis
  doi: 10.1093/cid/cit593
– volume: 50
  start-page: 138
  year: 2017
  ident: pntd.0012472.ref038
  article-title: Paracoccidioidomycosis in a liver transplant recipient
  publication-title: Rev Soc Bras Med Trop
  doi: 10.1590/0037-8682-0282-2016
– volume: 35
  start-page: e00233
  year: 2022
  ident: pntd.0012472.ref052
  article-title: Paracoccidioidomycosis: Current Status and Future Trends.
  publication-title: Clin Microbiol Rev
– volume: 8
  start-page: 1098
  year: 2022
  ident: pntd.0012472.ref051
  article-title: Paracoccidioidomycosis: What We Know and What Is New in Epidemiology, Diagnosis, and Treatment.
  publication-title: J Fungi.
  doi: 10.3390/jof8101098
– volume: 129
  start-page: 340
  year: 1984
  ident: pntd.0012472.ref032
  article-title: Paracoccidioidomycosis in the immunosuppressed host: report of a case and review of the literature
  publication-title: Am Rev Respir Dis
– volume: 55
  start-page: e0110
  year: 2022
  ident: pntd.0012472.ref045
  article-title: Disseminated paracoccidioidomycosis with skull and mandible involvement in a heart transplant recipient
  publication-title: Rev Soc Bras Med Trop
  doi: 10.1590/0037-8682-0110-2022
– volume: 83
  start-page: 863
  year: 2023
  ident: pntd.0012472.ref031
  article-title: Evaluation of an enzyme immunoassay technique on detecting urinary Histoplasma capsulatum antigen in the diagnosis of disseminated histoplasmosis in Argentina.
  publication-title: Medicina (Mex).
– volume: 47
  start-page: 1048
  year: 2015
  ident: pntd.0012472.ref035
  article-title: A Rare Paracoccidioidomycosis Diagnosis in a Kidney Transplant Receptor: Case Report
  publication-title: Transplant Proc
  doi: 10.1016/j.transproceed.2015.03.006
– volume: 187
  start-page: 129
  year: 2022
  ident: pntd.0012472.ref030
  article-title: Evaluation of OIDx Histoplasma Urinary Antigen EIA
  publication-title: Mycopathologia
  doi: 10.1007/s11046-021-00602-9
– volume: 16
  start-page: 165
  year: 2022
  ident: pntd.0012472.ref005
  article-title: Updates on Histoplasmosis in Solid Organ Transplantation.
  publication-title: Curr Fungal Infect Rep
  doi: 10.1007/s12281-022-00441-1
– volume: 43
  start-page: 209
  year: 2023
  ident: pntd.0012472.ref012
  article-title: Point-of-Care Testing for the Diagnosis of Fungal Infections.
  publication-title: Clin Lab Med.
  doi: 10.1016/j.cll.2023.02.005
– volume: 33
  start-page: 411
  year: 1995
  ident: pntd.0012472.ref033
  article-title: Paracoccidioidomycosis in a renal transplant recipient
  publication-title: Med Mycol
  doi: 10.1080/02681219580000781
– volume: 53
  start-page: 176
  year: 2010
  ident: pntd.0012472.ref054
  article-title: Is the geographical origin of a Paracoccidioides brasiliensis isolate important for antigen production for regional diagnosis of paracoccidioidomycosis?
  publication-title: Mycoses.
  doi: 10.1111/j.1439-0507.2008.01687.x
– volume: 23
  start-page: 1917
  year: 2017
  ident: pntd.0012472.ref018
  article-title: Paracoccidioidomycosis after Highway Construction, Rio de Janeiro, Brazil
  publication-title: Emerg Infect Dis
  doi: 10.3201/eid2311.170934
– volume: 62
  start-page: 77
  year: 1977
  ident: pntd.0012472.ref055
  article-title: Paracoccidioides brasiliensis: cell wall structure and virulence. A review
  publication-title: Mycopathologia
  doi: 10.1007/BF01259396
– volume: 33
  start-page: e13553
  year: 2019
  ident: pntd.0012472.ref004
  article-title: the AST Infectious Diseases Community of Practice. Endemic fungal infections in solid organ transplant recipients—Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice
  publication-title: Clin Transplant
  doi: 10.1111/ctr.13553
– volume: 7
  start-page: 12
  year: 2020
  ident: pntd.0012472.ref010
  article-title: Current and New Perspectives in the Diagnosis of Blastomycosis and Histoplasmosis.
  publication-title: J Fungi.
  doi: 10.3390/jof7010012
– start-page: 17
  year: 2017
  ident: pntd.0012472.ref008
– volume: 35
  start-page: 2618
  year: 1997
  ident: pntd.0012472.ref023
  article-title: Development of a novel antigen detection test for histoplasmosis
  publication-title: J Clin Microbiol
  doi: 10.1128/jcm.35.10.2618-2622.1997
– volume: 17
  start-page: 62
  year: 2010
  ident: pntd.0012472.ref020
  article-title: Validation and Clinical Application of a Molecular Method for Identification of Histoplasma capsulatum in Human Specimens in Colombia
  publication-title: South America. Clin Vaccine Immunol
  doi: 10.1128/CVI.00332-09
– volume: 54
  start-page: 111
  year: 1974
  ident: pntd.0012472.ref057
  article-title: Chemical and immunological properties of galactomannans obtained from Histoplasma duboisii, Histoplasma capsulatum, Paracoccidioides brasiliensis and Blasomyces dermatitidis.
  publication-title: Mycopathol Mycol Appl
  doi: 10.1007/BF02055979
– volume: 88
  start-page: 24
  year: 1995
  ident: pntd.0012472.ref040
  article-title: Causes of death in renal transplant recipients: a study of 102 autopsies from 1968 to 1991.
  publication-title: J R Soc Med
– volume: 30
  start-page: 42
  year: 2023
  ident: pntd.0012472.ref009
  article-title: Diagnosis of invasive fungal infections: challenges and recent developments
  publication-title: J Biomed Sci
  doi: 10.1186/s12929-023-00926-2
– volume: 6
  start-page: 293
  year: 2020
  ident: pntd.0012472.ref059
  article-title: Molecular Tools for Detection and Identification of Paracoccidioides Species: Current Status and Future Perspectives.
  publication-title: J Fungi.
  doi: 10.3390/jof6040293
– volume: 32
  start-page: 25
  year: 2021
  ident: pntd.0012472.ref042
  article-title: Mixed and disseminated paracoccidioidomycosis after liver transplantation: Case report
  publication-title: Med Mycol Case Rep
  doi: 10.1016/j.mmcr.2021.02.004
– volume: 5
  start-page: 2
  year: 2018
  ident: pntd.0012472.ref006
  article-title: Paracoccidioidomycosis in Immunocompromised Patients: A Literature Review.
  publication-title: J Fungi.
  doi: 10.3390/jof5010002
– volume: 21
  start-page: 1364
  year: 2014
  ident: pntd.0012472.ref026
  article-title: Validation of an Enzyme-Linked Immunosorbent Assay That Detects Histoplasma capsulatum Antigenuria in Colombian Patients with AIDS for Diagnosis and Follow-Up during Therapy
  publication-title: Clin Vaccine Immunol
  doi: 10.1128/CVI.00101-14
– volume: 46
  start-page: 279
  year: 2004
  ident: pntd.0012472.ref034
  article-title: Paracoccidioidomycosis in organ transplant recipient: case report.
  publication-title: Rev Inst Med Trop São Paulo
  doi: 10.1590/S0036-46652004000500009
– volume: 88
  start-page: e02010
  year: 2022
  ident: pntd.0012472.ref002
  article-title: Considerations about the Geographic Distribution of Histoplasma Species. Vives M, editor
  publication-title: Appl Environ Microbiol
  doi: 10.1128/aem.02010-21
– volume: 128
  start-page: 18
  year: 2007
  ident: pntd.0012472.ref021
  article-title: Performance Characteristics of a Polyclonal Enzyme Immunoassay for the Quantitation of Histoplasma Antigen in Human Urine Samples
  publication-title: Am J Clin Pathol
  doi: 10.1309/Q7879TYDW5D93QK7
– volume: 96
  start-page: 346
  year: 2021
  ident: pntd.0012472.ref043
  article-title: Disseminated paracoccidioidomycosis in a liver transplant patient
  publication-title: An Bras Dermatol
  doi: 10.1016/j.abd.2020.07.011
– volume: 31
  start-page: 1032
  year: 2000
  ident: pntd.0012472.ref047
  article-title: Paracoccidioidomycosis: A Model for Evaluation of the Effects of Human Immunodeficiency Virus Infection on the Natural History of Endemic Tropical Diseases
  publication-title: Clin Infect Dis
  doi: 10.1086/318146
– volume: 23
  start-page: 1135
  year: 2023
  ident: pntd.0012472.ref011
  article-title: An update on current and novel molecular diagnostics for the diagnosis of invasive fungal infections
  publication-title: Expert Rev Mol Diagn
  doi: 10.1080/14737159.2023.2267977
– volume: 53
  start-page: 448
  year: 2011
  ident: pntd.0012472.ref013
  article-title: A Multicenter Evaluation of Tests for Diagnosis of Histoplasmosis
  publication-title: Clin Infect Dis
  doi: 10.1093/cid/cir435
– volume: 38
  start-page: 2909
  year: 2000
  ident: pntd.0012472.ref022
  article-title: Comparison of an Established Antibody Sandwich Method with an Inhibition Method of Histoplasma capsulatum Antigen Detection
  publication-title: J Clin Microbiol
  doi: 10.1128/JCM.38.8.2909-2913.2000
– volume: 18
  start-page: 1333
  year: 2018
  ident: pntd.0012472.ref003
  article-title: Paracoccidioides spp. and Histoplasma capsulatum: Current and New Perspectives for Diagnosis and Treatment
  publication-title: Curr Top Med Chem
  doi: 10.2174/1568026618666181002112231
– volume: 19
  start-page: e12655
  year: 2017
  ident: pntd.0012472.ref037
  article-title: Acute pulmonary involvement by paracoccidiodomycosis disease immediately after kidney transplantation: Case report and literature review
  publication-title: Transpl Infect Dis
  doi: 10.1111/tid.12655
– volume: 58
  year: 2016
  ident: pntd.0012472.ref036
  article-title: PARACOCCIDIOIDOMYCOSIS IN A RENAL TRANSPLANT RECIPIENT.
  publication-title: Rev Inst Med Trop São Paulo [Internet].
– volume: 9
  start-page: 946
  year: 2023
  ident: pntd.0012472.ref048
  article-title: Trends in the Epidemiological and Clinical Profile of Paracoccidioidomycosis in the Endemic Area of Rio de Janeiro, Brazil.
  publication-title: J Fungi.
  doi: 10.3390/jof9090946
– volume: 17
  start-page: e0011645
  year: 2023
  ident: pntd.0012472.ref050
  article-title: Paracoccidioidomycosis and pregnancy: A 40-year single-center cohort study in the endemic area of Rio de Janeiro, Brazil.
  publication-title: PLoS Negl Trop Dis.
  doi: 10.1371/journal.pntd.0011645
– volume: 8
  start-page: e3174
  year: 2014
  ident: pntd.0012472.ref053
  article-title: Serological Diagnosis of Paracoccidioidomycosis: High Rate of Inter-laboratorial Variability among Medical Mycology Reference Centers.
  publication-title: PLoS Negl Trop Dis.
  doi: 10.1371/journal.pntd.0003174
– volume: 101
  start-page: 1100
  year: 2019
  ident: pntd.0012472.ref039
  article-title: Case Report: Paracoccidioidomycosis in Solid Organ Transplantation: Disseminated Disease in a Liver Recipient and Literature Review
  publication-title: Am J Trop Med Hyg
  doi: 10.4269/ajtmh.18-1008
– volume: 40
  start-page: 822
  year: 2008
  ident: pntd.0012472.ref041
  article-title: Bacterial and Fungal Pneumonias After Lung Transplantation
  publication-title: Transplant Proc
  doi: 10.1016/j.transproceed.2008.02.049
– volume: 16
  start-page: e0010529
  year: 2022
  ident: pntd.0012472.ref049
  article-title: Paracoccidioidomycosis in people living with HIV/AIDS: A historical retrospective cohort study in a national reference center for infectious diseases, Rio de Janeiro, Brazil.
  publication-title: PLoS Negl Trop Dis.
  doi: 10.1371/journal.pntd.0010529
– volume: 7
  start-page: 799
  year: 2021
  ident: pntd.0012472.ref028
  article-title: Validation and Concordance Analysis of a New Lateral Flow Assay for Detection of Histoplasma Antigen in Urine.
  publication-title: J Fungi.
  doi: 10.3390/jof7100799
– volume: 35
  start-page: 2252
  year: 1997
  ident: pntd.0012472.ref024
  article-title: Comparison of radioimmunoassay and enzyme-linked immunoassay methods for detection of Histoplasma capsulatum var. capsulatum antigen
  publication-title: J Clin Microbiol
  doi: 10.1128/jcm.35.9.2252-2255.1997
– volume: 16
  start-page: 852
  year: 2009
  ident: pntd.0012472.ref025
  article-title: Development and Evaluation of an Enzyme-Linked Immunosorbent Assay To Detect Histoplasma capsulatum Antigenuria in Immunocompromised Patients.
  publication-title: Clin Vaccine Immunol
  doi: 10.1128/CVI.00066-09
– year: 2015
  ident: pntd.0012472.ref046
  article-title: Why the communicable/non-communicable disease dichotomy is problematic for public health control strategies: implications of multimorbidity for health systems in an era of health transition.
  publication-title: Int Health.
– volume: 24
  start-page: 445
  year: 1986
  ident: pntd.0012472.ref056
  article-title: A comparative histopathological, immunological, and biochemical study of experimental intravenous paracoccidioidomycosis induced in mice by three Paracoccidioides brasiliensis isolates
  publication-title: J Med Vet Mycol Bi-Mon Publ Int Soc Hum Anim Mycol
– year: 2020
  ident: pntd.0012472.ref019
  article-title: Solid organ transplantation in Brazil: a descriptive study of distribution and access inequalities across the Brazilian territory, 2001–2017.
  publication-title: Epidemiol E Serviços Saúde [Internet].
– volume: 21
  start-page: e364
  year: 2021
  ident: pntd.0012472.ref058
  article-title: Global guideline for the diagnosis and management of the endemic mycoses: an initiative of the European Confederation of Medical Mycology in cooperation with the International Society for Human and Animal Mycology
  publication-title: Lancet Infect Dis
  doi: 10.1016/S1473-3099(21)00191-2
– volume: 14
  start-page: 1587
  year: 2007
  ident: pntd.0012472.ref016
  article-title: Detection of Histoplasma Antigen by a Quantitative Enzyme Immunoassay.
  publication-title: Clin Vaccine Immunol
  doi: 10.1128/CVI.00071-07
– volume: 6
  start-page: 23
  year: 2012
  ident: pntd.0012472.ref007
  article-title: Epidemiology of Invasive Fungal Infections in Latin America.
  publication-title: Curr Fungal Infect Rep.
  doi: 10.1007/s12281-011-0081-7
– volume: 50
  start-page: 715
  year: 2017
  ident: pntd.0012472.ref001
  article-title: Brazilian guidelines for the clinical management of paracoccidioidomycosis.
  publication-title: Rev Soc Bras Med Trop
  doi: 10.1590/0037-8682-0230-2017
– volume: 8
  year: 2021
  ident: pntd.0012472.ref029
  article-title: Diagnosis of Histoplasmosis Using the MVista Histoplasma Galactomannan Antigen Qualitative Lateral Flow–Based Immunoassay: A Multicenter Study.
  publication-title: Open Forum Infect Dis
– year: 2021
  ident: pntd.0012472.ref044
  article-title: Disseminated Paracoccidioidomycosis in a Kidney Transplant Recipient.
  publication-title: Cureus [Internet].
– volume: 56
  start-page: e01959
  year: 2018
  ident: pntd.0012472.ref027
  article-title: Multicenter Validation of Commercial Antigenuria Reagents To Diagnose Progressive Disseminated Histoplasmosis in People Living with HIV/AIDS in Two Latin American Countries. Diekema DJ, editor
  publication-title: J Clin Microbiol
  doi: 10.1128/JCM.01959-17
SSID ssj0059581
Score 2.4195552
SecondaryResourceType review_article
Snippet Paracoccidioidomycosis (PCM) and histoplasmosis are endemic fungal diseases in South America. Both can lead to lung involvement with fungal dissemination...
Background Paracoccidioidomycosis (PCM) and histoplasmosis are endemic fungal diseases in South America. Both can lead to lung involvement with fungal...
Paracoccidioidomycosis (PCM) and histoplasmosis are severe fungal diseases occurring simultaneously in South America. They can cause similar clinical...
SourceID pubmedcentral
proquest
gale
pubmed
crossref
SourceType Open Access Repository
Aggregation Database
Index Database
Enrichment Source
StartPage e0012472
SubjectTerms Acute Disease
Analysis
Antigens, Fungal - immunology
Antigens, Fungal - urine
Biology and Life Sciences
Case studies
Cross Reactions
Diagnosis
False Positive Reactions
Galactose - analogs & derivatives
Histoplasma - immunology
Histoplasma capsulatum
Histoplasmosis
Histoplasmosis - complications
Histoplasmosis - immunology
Histoplasmosis - microbiology
Histoplasmosis - urine
Humans
Immunocompromised Host
Kidney Transplantation
Kidneys
Mannans - urine
Medicine and Health Sciences
Organ transplant recipients
Paracoccidioidomycosis
Paracoccidioidomycosis - complications
Paracoccidioidomycosis - diagnosis
Paracoccidioidomycosis - urine
Research and Analysis Methods
Transplant Recipients
Transplantation
Urine
Title Histoplasma capsulatum urinary antigen detection in a kidney transplant recipient with acute paracoccidioidomycosis: Case study and literature review
URI https://www.ncbi.nlm.nih.gov/pubmed/39208382
https://www.proquest.com/docview/3099799568
https://pubmed.ncbi.nlm.nih.gov/PMC11389928
Volume 18
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwhV1ba9swFBZdC6UvY_d56zINBntyiXWxrMEYXWgpg5QxFsibkSWbmTl2ljjQ_JD-353jG_VYGYG86Ch2zkX6pKPziZD3TLKEs2nmZ9JlvmBJAjHHrQ_mFy4BBMsFFifPr8Orhfi6lMsD0t_Z2ilw-8-lHd4ntdgUZze_958h4D81tzaooO90ti5rh5kFJhQMykcwNykM1bkY8gpSyyjoCuju63lCjgEzADKJ2Giu-nvEvjNljY9T3pmfLh-Rhx2wpOetJzwmB2n5hBzPu9T5U3LbEIKsASyvDLUGFseFqXcrirvtZrOnoGEk5qQurZvTWSXNS2ror9yV6Z7WDQd6AUIU6TDWWEVJcQ-XGrurU4oM4jC02tzlVe6q1d5W23z7kc5gkqQNhS08wNFiIHGmbc3MM7K4vPgxu_K7Oxl8C8ix9tMw4tbAstaESmilg0S66dROLceSgASsnmRcC4ekM1kiEUKAYkL4TA1Psow_J4dlVaYvCVUZC7VULJTSCWZ0pLSzgQUIyK3VofAI77Uf246wHO_NKOImC6dg4dKqNkbzxZ35POIPvdYtYcd_5N-iYeO27HSI9_g8gsEQsIviHvnQSKAPwvOt6QoX4F8gd9ZI8nQkCZFqR83veueJsQmPt5VptdvGHOuXscY48siL1pmGl--d0SPRyM0GASQIH7eU-c-GKDzALLRm0at7f_Q1OWGA0nCTnOlTclhvdukbQFl1MiEP1FLBdzQLJuToy8X1t--TZsdi0oTUH3vJMCQ
linkProvider Scholars Portal
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Histoplasma+capsulatum+urinary+antigen+detection+in+a+kidney+transplant+recipient+with+acute+paracoccidioidomycosis%3A+Case+study+and+literature+review&rft.jtitle=PLoS+neglected+tropical+diseases&rft.au=Oliveira+Bastos%2C+Matheus&rft.au=Varon%2C+Andr%C3%A9a+Gina&rft.au=Theodoro%2C+Pedro+Henrique+Nascimento&rft.au=Falc%C3%A3o%2C+Eduardo+Mastrangelo+Marinho&rft.date=2024-08-29&rft.eissn=1935-2735&rft.volume=18&rft.issue=8&rft.spage=e0012472&rft_id=info:doi/10.1371%2Fjournal.pntd.0012472&rft_id=info%3Apmid%2F39208382&rft.externalDocID=39208382
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1935-2735&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1935-2735&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1935-2735&client=summon