Hypermethylation of two CpG sites upstream of CASP8AP2 promoter influences gene expression and treatment outcome in childhood acute lymphoblastic leukemia - Li, Zhi-Gang; Jiao, Ying; Li, Wei-Jing; Deng, Guo-Ren; Cui, Lei; Gao, Chao; Zhao, Xiao-Xi; Wu, Min-Yuan; Jia, Hong-Ti (Leukemia research, 2013)
Keywords: Acute lymphoblastic leukemia; Adolescent; Antineoplastic Agents - therapeutic use; Apoptosis Regulatory Proteins - genetics; Calcium-Binding Proteins - genetics; CASP8AP2; Child; Child, Preschool; Childhood; CpG Islands; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Hematology, Oncology and Palliative Medicine; Humans; Infant; Male; Methylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy; Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics; Precursor Cell Lymphoblastic Leukemia-Lymphoma - mortality; Prognosis; Promoter Regions, Genetic; RNA, Messenger - genetics; RNA, Messenger - metabolism; CASP8AP2; Prognosis; Acute lymphoblastic leukemia; Methylation; Childhood