Sonic Hedgehog promotes in vitro oocyte maturation and term development of embryos in Taiwan native goats

• Published in: Theriogenology Vol. 103; pp. 52 - 58
• Main Authors: Wang, De-Chi, Huang, Jan-Chi, Lo, Neng-Wen, Chen, Lih-Ren, Mermillod, Pascal, Ma, Wen-Lung, Chiang, Hsin-I., Ju, Jyh-Cherng
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.11.2017; Elsevier
• Subjects: Animals; blastocyst; Cumulus Cells - metabolism; cyclopamine; Embryo Culture Techniques; Embryo Transfer; Embryo, Mammalian - physiology; embryogenesis; Embryonic Development - physiology; Epithelial Cells - metabolism; epithelium; Fallopian Tubes - cytology; Female; Fertilization in Vitro; follicular development; freeze-thaw cycles; Gene Expression Regulation, Developmental - drug effects; Gene Expression Regulation, Developmental - physiology; Goat; goats; Goats - embryology; Goats - metabolism; granulosa cells; Hedgehog Proteins - genetics; Hedgehog Proteins - metabolism; In Vitro Oocyte Maturation Techniques - veterinary; In vitro development; Life Sciences; mice; Oocyte maturation; oocytes; Other; Ovary - metabolism; oviducts; Random Allocation; Reproductive Biology; semen; signal transduction; slaughterhouses; Sonic Hedgehog; survival rate; Veratrum Alkaloids - pharmacology; zygote; Embryo transfer; In vitro development; Goat; Sonic Hedgehog; Oocyte maturation; Sonic hedgehog; développement in vitro; chèvre; maturation de l'ovocyte; nannygoats; In vitro development; reproduction animale; goat; transfert d'embryon; caprin

The aim of this study was to investigate the effects of Shh (Sonic Hedgehog) protein on caprine oocyte maturation, early embryo development, and developmental competence after embryo transfer of vitrified-thawed in vitro-produced embryos. Cumulus-oocyte complexes (COCs) derived from abattoir were ra...