Disturbed Gut-Liver axis indicating oral exposure to polystyrene microplastic potentially increases the risk of insulin resistance

• Published in: Environment international Vol. 164; p. 107273
• Main Authors: Shi, Chunzhen, Han, Xiaohong, Guo, Wei, Wu, Qi, Yang, Xiaoxi, Wang, Yuanyuan, Tang, Gang, Wang, Shunhao, Wang, Ziniu, Liu, Yaquan, Li, Min, Lv, Meilin, Guo, Yunhe, Li, Zikang, Li, Junya, Shi, Jianbo, Qu, Guangbo, Jiang, Guibin
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.06.2022; Elsevier
• Subjects: at-risk population; blood glucose; diabetes; environment; Gut-liver axis; humans; inflammation; insulin; Insulin resistance; intestines; kidneys; liver; metabolism; Metabolomics; Microbiome; Microplastic; microplastics; multiomics; oral exposure; placenta; polystyrenes; prognosis; risk; Metabolomics; Insulin resistance; Microplastic; Gut-liver axis; Microbiome

[Display omitted] •We established an association between microplastics exposure and the occurrence of a disease.•Our findings highlight the health risks of a subset of the population with high exposure to microplastics.•Our study is the first to find an increased risk of insulin resistance contribut...