Pre-diagnostic serum concentrations of organochlorines and risk of acute myeloid leukemia: A nested case-control study in the Norwegian Janus Serum Bank Cohort

• Published in: Environment international Vol. 125; pp. 229 - 235
• Main Authors: Bassig, Bryan A., Engel, Lawrence S., Langseth, Hilde, Grimsrud, Tom K., Cantor, Kenneth P., Vermeulen, Roel, Purdue, Mark P., Barr, Dana Boyd, Wong, Jason Y.Y., Blair, Aaron, Rothman, Nathaniel, Lan, Qing
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.04.2019; Elsevier
• Subjects: Acute myeloid leukemia; adults; blood serum; case-control studies; chlordane; confidence interval; DDT (pesticide); dieldrin; heptachlor; heptachlor epoxide; isomers; metabolites; myeloid leukemia; Norway; occupational exposure; odds ratio; Organochlorines; Pesticides; Polychlorinated biphenyls; regression analysis; risk; Norway; Polychlorinated biphenyls; Acute myeloid leukemia; Organochlorines; Pesticides

Epidemiologic studies suggest an increased risk of leukemia among individuals occupationally exposed to some organochlorine (OC) compounds. Associations between serum OC pesticide and polychlorinated biphenyl (PCB) levels and risk of acute myeloid leukemia (AML), the most common subtype of acute leu...