Consensus of experts from the French Society of Geriatrics and Gerontology on the management of heart failure in very old subjects
The prevalence of heart failure increases with age. In France, the 1-year mortality rate is 35% in subjects aged 80–89 years with heart failure, and 50% after the age of 90 years. In octogenarians, heart failure is associated with high rates of cardiovascular and non-cardiovascular events, and is on...
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Published in | Archives of cardiovascular diseases Vol. 114; no. 3; pp. 246 - 259 |
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Main Authors | , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Netherlands
Elsevier Masson SAS
01.03.2021
Elsevier ; Société française de cardiologie [2008-....] |
Subjects | |
Online Access | Get full text |
ISSN | 1875-2136 1875-2128 1875-2128 |
DOI | 10.1016/j.acvd.2020.12.001 |
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Abstract | The prevalence of heart failure increases with age. In France, the 1-year mortality rate is 35% in subjects aged 80–89 years with heart failure, and 50% after the age of 90 years. In octogenarians, heart failure is associated with high rates of cardiovascular and non-cardiovascular events, and is one of the main causes of hospitalization and disability. The prevalence of frailty increases in elderly subjects with heart failure, and the co-occurrence of heart failure and frailty increases the risk of mortality in patients with heart failure. In the elderly, the presence of frailty must be evaluated using a comprehensive geriatric assessment to manage geriatric syndromes, such as cognitive disorders, malnutrition, falls, depression, polypharmacy, disability and social isolation. The objective of heart failure therapy in octogenarians is to reduce symptoms, mortality and hospitalizations, but also to improve quality of life. In the absence of specific studies involving very old subjects, most recommendations are extrapolated from evidence-based data from younger populations. Overall, the epidemiological studies in patients with heart failure aged>80 years highlight the underprescription of recommended drugs. This underprescription may be related to comorbidity, a fear of side-effects and the lack of specific recommendations for drug prescription in heart failure with preserved ejection fraction, which is common in this very old population. The benefit/risk ratio related to heart failure treatment and comorbidity should be carefully weighed and reassessed on a regular basis. Consideration of disease prognosis according to factors that predict mortality can help to better define the care plan and promote palliative and supportive care when needed.
La prévalence de l’insuffisance cardiaque (IC) augmente avec l’âge. En France, la mortalité à un an est de 35 % chez les insuffisants cardiaques âgés de 80 à 89 ans et de 50 % après 90 ans. Chez les octogénaires, l’IC est associée à un risque élevé d’événements cardiovasculaires, mais aussi d’événements non cardiovasculaires, elle représente ainsi l’une des principales causes d’hospitalisation et de perte d’autonomie. La prévalence de la fragilité augmente chez les sujets âgés insuffisants cardiaques et la fragilité augmente le risque de mortalité des insuffisants cardiaques. Chez les personnes âgées, l’existence d’une fragilité doit faire réaliser une évaluation gériatrique multidimensionnelle afin de prendre en charge les syndromes gériatriques comme les troubles cognitifs, les chutes, la dénutrition, la dépression, la iatrogénie, la perte d’autonomie et l’isolement social. L’objectif du traitement de l’insuffisance cardiaque après 80 ans est de réduire les symptômes, la mortalité et les hospitalisations, mais aussi d’améliorer la qualité de vie. En l’absence d’études spécifiques réalisées chez des sujets très âgés, la plupart des recommandations sont extrapolées à partir de données provenant de populations plus jeunes. Globalement, les études épidémiologiques indiquent une prescription insuffisante des médicaments recommandés dans l’insuffisance cardiaque, alors que les bénéfices des traitements sont pourtant observés indépendamment de l’âge. Cette sous-prescription peut être liée aux comorbidités et à la peur des effets secondaires ou à l’absence de recommandations spécifiques dans le cadre de l’IC à fraction d’éjection préservée fréquente dans cette population. Le rapport bénéfices/risques des médicaments de l’insuffisance cardiaque doit être évalué régulièrement au cours du suivi. La prise en compte du pronostic de la maladie en fonction des facteurs prédictifs de mortalité peut aider à mieux définir le plan de soins et à promouvoir des soins palliatifs si besoin. |
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AbstractList | The prevalence of heart failure increases with age. In France, the 1-year mortality rate is 35% in subjects aged 80–89 years with heart failure, and 50% after the age of 90 years. In octogenarians, heart failure is associated with high rates of cardiovascular and non-cardiovascular events, and is one of the main causes of hospitalization and disability. The prevalence of frailty increases in elderly subjects with heart failure, and the co-occurrence of heart failure and frailty increases the risk of mortality in patients with heart failure. In the elderly, the presence of frailty must be evaluated using a comprehensive geriatric assessment to manage geriatric syndromes, such as cognitive disorders, malnutrition, falls, depression, polypharmacy, disability and social isolation. The objective of heart failure therapy in octogenarians is to reduce symptoms, mortality and hospitalizations, but also to improve quality of life. In the absence of specific studies involving very old subjects, most recommendations are extrapolated from evidence-based data from younger populations. Overall, the epidemiological studies in patients with heart failure aged>80 years highlight the underprescription of recommended drugs. This underprescription may be related to comorbidity, a fear of side-effects and the lack of specific recommendations for drug prescription in heart failure with preserved ejection fraction, which is common in this very old population. The benefit/risk ratio related to heart failure treatment and comorbidity should be carefully weighed and reassessed on a regular basis. Consideration of disease prognosis according to factors that predict mortality can help to better define the care plan and promote palliative and supportive care when needed.
La prévalence de l’insuffisance cardiaque (IC) augmente avec l’âge. En France, la mortalité à un an est de 35 % chez les insuffisants cardiaques âgés de 80 à 89 ans et de 50 % après 90 ans. Chez les octogénaires, l’IC est associée à un risque élevé d’événements cardiovasculaires, mais aussi d’événements non cardiovasculaires, elle représente ainsi l’une des principales causes d’hospitalisation et de perte d’autonomie. La prévalence de la fragilité augmente chez les sujets âgés insuffisants cardiaques et la fragilité augmente le risque de mortalité des insuffisants cardiaques. Chez les personnes âgées, l’existence d’une fragilité doit faire réaliser une évaluation gériatrique multidimensionnelle afin de prendre en charge les syndromes gériatriques comme les troubles cognitifs, les chutes, la dénutrition, la dépression, la iatrogénie, la perte d’autonomie et l’isolement social. L’objectif du traitement de l’insuffisance cardiaque après 80 ans est de réduire les symptômes, la mortalité et les hospitalisations, mais aussi d’améliorer la qualité de vie. En l’absence d’études spécifiques réalisées chez des sujets très âgés, la plupart des recommandations sont extrapolées à partir de données provenant de populations plus jeunes. Globalement, les études épidémiologiques indiquent une prescription insuffisante des médicaments recommandés dans l’insuffisance cardiaque, alors que les bénéfices des traitements sont pourtant observés indépendamment de l’âge. Cette sous-prescription peut être liée aux comorbidités et à la peur des effets secondaires ou à l’absence de recommandations spécifiques dans le cadre de l’IC à fraction d’éjection préservée fréquente dans cette population. Le rapport bénéfices/risques des médicaments de l’insuffisance cardiaque doit être évalué régulièrement au cours du suivi. La prise en compte du pronostic de la maladie en fonction des facteurs prédictifs de mortalité peut aider à mieux définir le plan de soins et à promouvoir des soins palliatifs si besoin. The prevalence of heart failure increases with age. In France, the 1-year mortality rate is 35% in subjects aged 80-89 years with heart failure, and 50% after the age of 90 years. In octogenarians, heart failure is associated with high rates of cardiovascular and non-cardiovascular events, and is one of the main causes of hospitalization and disability. The prevalence of frailty increases in elderly subjects with heart failure, and the co-occurrence of heart failure and frailty increases the risk of mortality in patients with heart failure. In the elderly, the presence of frailty must be evaluated using a comprehensive geriatric assessment to manage geriatric syndromes, such as cognitive disorders, malnutrition, falls, depression, polypharmacy, disability and social isolation. The objective of heart failure therapy in octogenarians is to reduce symptoms, mortality and hospitalizations, but also to improve quality of life. In the absence of specific studies involving very old subjects, most recommendations are extrapolated from evidence-based data from younger populations. Overall, the epidemiological studies in patients with heart failure aged>80 years highlight the underprescription of recommended drugs. This underprescription may be related to comorbidity, a fear of side-effects and the lack of specific recommendations for drug prescription in heart failure with preserved ejection fraction, which is common in this very old population. The benefit/risk ratio related to heart failure treatment and comorbidity should be carefully weighed and reassessed on a regular basis. Consideration of disease prognosis according to factors that predict mortality can help to better define the care plan and promote palliative and supportive care when needed.The prevalence of heart failure increases with age. In France, the 1-year mortality rate is 35% in subjects aged 80-89 years with heart failure, and 50% after the age of 90 years. In octogenarians, heart failure is associated with high rates of cardiovascular and non-cardiovascular events, and is one of the main causes of hospitalization and disability. The prevalence of frailty increases in elderly subjects with heart failure, and the co-occurrence of heart failure and frailty increases the risk of mortality in patients with heart failure. In the elderly, the presence of frailty must be evaluated using a comprehensive geriatric assessment to manage geriatric syndromes, such as cognitive disorders, malnutrition, falls, depression, polypharmacy, disability and social isolation. The objective of heart failure therapy in octogenarians is to reduce symptoms, mortality and hospitalizations, but also to improve quality of life. In the absence of specific studies involving very old subjects, most recommendations are extrapolated from evidence-based data from younger populations. Overall, the epidemiological studies in patients with heart failure aged>80 years highlight the underprescription of recommended drugs. This underprescription may be related to comorbidity, a fear of side-effects and the lack of specific recommendations for drug prescription in heart failure with preserved ejection fraction, which is common in this very old population. The benefit/risk ratio related to heart failure treatment and comorbidity should be carefully weighed and reassessed on a regular basis. Consideration of disease prognosis according to factors that predict mortality can help to better define the care plan and promote palliative and supportive care when needed. The prevalence of heart failure increases with age. In France, the 1-year mortality rate is 35% in subjects aged 80-89 years with heart failure, and 50% after the age of 90 years. In octogenarians, heart failure is associated with high rates of cardiovascular and non-cardiovascular events, and is one of the main causes of hospitalization and disability. The prevalence of frailty increases in elderly subjects with heart failure, and the co-occurrence of heart failure and frailty increases the risk of mortality in patients with heart failure. In the elderly, the presence of frailty must be evaluated using a comprehensive geriatric assessment to manage geriatric syndromes, such as cognitive disorders, malnutrition, falls, depression, polypharmacy, disability and social isolation. The objective of heart failure therapy in octogenarians is to reduce symptoms, mortality and hospitalizations, but also to improve quality of life. In the absence of specific studies involving very old subjects, most recommendations are extrapolated from evidence-based data from younger populations. Overall, the epidemiological studies in patients with heart failure aged>80 years highlight the underprescription of recommended drugs. This underprescription may be related to comorbidity, a fear of side-effects and the lack of specific recommendations for drug prescription in heart failure with preserved ejection fraction, which is common in this very old population. The benefit/risk ratio related to heart failure treatment and comorbidity should be carefully weighed and reassessed on a regular basis. Consideration of disease prognosis according to factors that predict mortality can help to better define the care plan and promote palliative and supportive care when needed. |
Author | Chassagne, Philippe Jeandel, Claude Benetos, Athanase Krolak-Salmon, Pierre Hanon, Olivier Belmin, Joël Nourhashemi, Fati De Decker, Laure Paccalin, Marc |
Author_xml | – sequence: 1 givenname: Olivier surname: Hanon fullname: Hanon, Olivier email: olivier.hanon@aphp.fr organization: Service de gériatrie, hôpital Broca, AP–HP, 75013 Paris, France – sequence: 2 givenname: Joël surname: Belmin fullname: Belmin, Joël organization: Service de gériatrie, hôpital Charles-Foix, 94200 Ivry-sur-Seine, France – sequence: 3 givenname: Athanase surname: Benetos fullname: Benetos, Athanase organization: Service de médecine interne gériatrique, CHRU plurithématiques-Nancy, 54035 Nancy, France – sequence: 4 givenname: Philippe surname: Chassagne fullname: Chassagne, Philippe organization: Service de médecine interne gériatrique, CHU de Rouen, 76000 Rouen, France – sequence: 5 givenname: Laure surname: De Decker fullname: De Decker, Laure organization: Service de gérontologie clinique, CHU de Nantes, 44093 Nantes, France – sequence: 6 givenname: Claude surname: Jeandel fullname: Jeandel, Claude organization: Centre Antonin-Balmès, CHU de Montpellier, 34090 Montpellier, France – sequence: 7 givenname: Pierre surname: Krolak-Salmon fullname: Krolak-Salmon, Pierre organization: Institut du vieillissement, hôpital des Charpennes, hospices civils de Lyon, 69002 Lyon, France – sequence: 8 givenname: Fati surname: Nourhashemi fullname: Nourhashemi, Fati organization: Gérontopôle, CHU de Toulouse, 31059 Toulouse, France – sequence: 9 givenname: Marc surname: Paccalin fullname: Paccalin, Marc organization: Pôle de Gériatrie, CHU La Milétrie, 86021 Poitiers, France |
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Snippet | The prevalence of heart failure increases with age. In France, the 1-year mortality rate is 35% in subjects aged 80–89 years with heart failure, and 50% after... The prevalence of heart failure increases with age. In France, the 1-year mortality rate is 35% in subjects aged 80-89 years with heart failure, and 50% after... |
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SubjectTerms | Age Factors Aged, 80 and over Cardiology Cardiology - standards Cardiovascular Agents Cardiovascular Agents - adverse effects Cardiovascular Agents - therapeutic use Clinical Decision-Making Comorbidity Consensus Decision Support Techniques Elderly Female Frail Elderly Geriatrics Geriatrics - standards Gériatrie Health Status Heart Failure Heart Failure - diagnosis Heart Failure - drug therapy Heart Failure - mortality Heart Failure - physiopathology Humans Insuffisance cardiaque Life Sciences Male Palliative Care Prevalence Quality of Life Recovery of Function Risk Assessment Risk Factors Sujet âgé Treatment Outcome |
Title | Consensus of experts from the French Society of Geriatrics and Gerontology on the management of heart failure in very old subjects |
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