In Vitro Evaluation of Different Prebiotics on the Modulation of Gut Microbiota Composition and Function in Morbid Obese and Normal-Weight Subjects

• Published in: International Journal of Molecular Sciences Vol. 21; no. 3; p. 906
• Main Authors: Nogacka, Alicja M., Salazar, Nuria, Arboleya, Silvia, Ruas-Madiedo, Patricia, Mancabelli, Leonardo, Suarez, Adolfo, Martinez-Faedo, Ceferino, Ventura, Marco, Tochio, Takumi, Hirano, Katsuaki, Endo, Akihito, G. de los Reyes-Gavilán, Clara, Gueimonde, Miguel
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 30.01.2020; MDPI
• Subjects: Adult; Bacteria; Bifidobacterial-ITS; Carbohydrates; Carbon; Case-Control Studies; Feces; Female; Fermentation; Functionality; Gas production; Gases; Gastrointestinal Microbiome; Glucose; Gut microbiota; HT29; Humans; In vitro model; In vitro models; In Vitro Techniques; Male; Metabolism; Microbiota; Microorganisms; Obesity; Obesity, Morbid; Population; Prebiotic; Prebiotics; RTCA; SCFA; Thinness; Weight control; microbiota; in vitro model; HT29; gas production; RTCA; prebiotics; functionality; SCFA; bifidobacterial-ITS; obesity

The gut microbiota remains relatively stable during adulthood; however, certain intrinsic and environmental factors can lead to microbiota dysbiosis. Its restoration towards a healthy condition using best-suited prebiotics requires previous development of in vitro models for evaluating their functio...