Systematic Comparison of Two Animal-to-Human Transmitted Human Coronaviruses: SARS-CoV-2 and SARS-CoV

• Published in: Viruses Vol. 12; no. 2; p. 244
• Main Authors: Xu, Jiabao, Zhao, Shizhe, Teng, Tieshan, Abdalla, Abualgasim Elgaili, Zhu, Wan, Xie, Longxiang, Wang, Yunlong, Guo, Xiangqian
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI 22.02.2020; MDPI AG
• Subjects: Animals; Betacoronavirus - chemistry; Betacoronavirus - genetics; Betacoronavirus - pathogenicity; China - epidemiology; Chiroptera - virology; clinical manifestations; Communication; Coronavirus Infections - diagnosis; Coronavirus Infections - epidemiology; Coronavirus Infections - therapy; Coronavirus Infections - virology; coronaviruses; COVID-19; Disease Reservoirs; Disease Susceptibility; Eutheria - virology; Genome, Viral; genomic comparison; Global Health; Humans; Infectious Disease Incubation Period; pathogenic mechanism; Pneumonia, Viral - diagnosis; Pneumonia, Viral - epidemiology; Pneumonia, Viral - therapy; Pneumonia, Viral - virology; Proteome; proteomic comparison; sars-cov; SARS-CoV-2; Sequence Alignment; Severe Acute Respiratory Syndrome - diagnosis; Severe Acute Respiratory Syndrome - epidemiology; Severe Acute Respiratory Syndrome - therapy; Severe Acute Respiratory Syndrome - virology; Severe acute respiratory syndrome-related coronavirus - chemistry; Severe acute respiratory syndrome-related coronavirus - genetics; Severe acute respiratory syndrome-related coronavirus - pathogenicity; Viral Proteins; China; SARS-CoV-2; clinical manifestations; proteomic comparison; genomic comparison; pathogenic mechanism; SARS-CoV; coronaviruses

After the outbreak of the severe acute respiratory syndrome (SARS) in the world in 2003, human coronaviruses (HCoVs) have been reported as pathogens that cause severe symptoms in respiratory tract infections. Recently, a new emerged HCoV isolated from the respiratory epithelium of unexplained pneumo...