Brefeldin A—A Major Pathogenic Factor of Peanut Pod Rot from Fusarium neocosmosporiellum

• Published in: Toxins Vol. 16; no. 12; p. 548
• Main Authors: Wang, Huiling, Wang, Xiaohan, Han, Huiling, Yu, Quanlin, Tan, Xinmiao, Liu, Junlong, Zhao, Yiting, Sun, Weiming
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.12.2024; MDPI
• Subjects: Agricultural production; Antibiotics; Arachis - microbiology; Beans; Brefeldin A; Brefeldin A - pharmacology; Communication; Disease; Elongation; Fungi; Fusarium; Fusarium neocosmosporiellum; Ionization; Legumes; Mass spectrometry; Mass spectroscopy; Mimosaceae; mycotoxins; NMR; Nuclear magnetic resonance; Oryza - microbiology; Pathogenicity; Pathogens; peanut pod rot; Peanuts; Phytotoxicity; Plant diseases; Plant Diseases - microbiology; Pod rot; Raphanus - microbiology; Rice; Seeds; Seeds - microbiology; Toxicity; Toxins; Vigna - microbiology; China; Hebei China; peanut pod rot; brefeldin A; phytotoxicity; Fusarium neocosmosporiellum; mycotoxins

Fusarium neocosmosporiellum is the main pathogen of peanut pod rot in China. To investigate the type of F. neocosmosporiellum toxin and its pathogenic mechanism, a macrolide, brefeldin A, was isolated. The structure of the compound was identified by 1D and 2D nuclear magnetic resonance (NMR) and hig...