Ridge Preservation Using Demineralized Bone Matrix Gel With Recombinant Human Bone Morphogenetic Protein-2 After Tooth Extraction: A Randomized Controlled Clinical Trial

• Published in: Journal of oral and maxillofacial surgery Vol. 72; no. 7; pp. 1281 - 1290
• Main Authors: Kim, Yu-Jin, Lee, Jeong-Yol, Kim, Jong-Eun, Park, Jung-Chul, Shin, Sang-Wan, Cho, Kyoo-Sung
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.07.2014
• Subjects: Adult; Alveolar Bone Loss - prevention & control; Alveolar Process - diagnostic imaging; Alveolar Process - surgery; Bone Morphogenetic Protein 2 - administration & dosage; Bone Morphogenetic Protein 2 - therapeutic use; Female; Humans; Male; Middle Aged; Prospective Studies; Recombinant Proteins - administration & dosage; Recombinant Proteins - therapeutic use; Single-Blind Method; Surgery; Tomography, X-Ray Computed; Tooth Extraction - adverse effects; Transforming Growth Factor beta - administration & dosage; Transforming Growth Factor beta - therapeutic use

The aim of the present randomized controlled trial was to determine the safety and efficacy of injectable demineralized bone matrix (DBM) gel combined with recombinant human bone morphogenetic protein-2 (rhBMP-2) on alveolar ridge preservation after tooth extraction. A total of 69 patients were rand...