Phosphate-Binding Agents in Adults With CKD: A Network Meta-analysis of Randomized Trials

• Published in: American journal of kidney diseases Vol. 68; no. 5; pp. 691 - 702
• Main Authors: Palmer, Suetonia C., Gardner, Sharon, Tonelli, Marcello, Mavridis, Dimitris, Johnson, David W., Craig, Jonathan C., French, Richard, Ruospo, Marinella, Strippoli, Giovanni F.M.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.11.2016
• Subjects: Adult; calcium; Chelating Agents - therapeutic use; chronic kidney disease (CKD); Humans; iron; lanthanum; Lanthanum - therapeutic use; meta-analysis; mortality; Nephrology; phosphate binder; Phosphate-binding agents; Phosphates; Randomized Controlled Trials as Topic; Renal Insufficiency, Chronic - drug therapy; sevelamer; Sevelamer - therapeutic use; calcium; lanthanum; Phosphate-binding agents; mortality; meta-analysis; phosphate binder; sevelamer; iron; chronic kidney disease (CKD)

Guidelines preferentially recommend noncalcium phosphate binders in adults with chronic kidney disease (CKD). We compare and rank phosphate-binder strategies for CKD. Network meta-analysis. Adults with CKD. Randomized trials with allocation to phosphate binders. Sevelamer, lanthanum, iron, calcium,...