Genetic factors exist behind the high prevalence of reduced high-density lipoprotein cholesterol levels in the Roma population

• Published in: Atherosclerosis Vol. 263; pp. 119 - 126
• Main Authors: Pikó, Péter, Fiatal, Szilvia, Kósa, Zsigmond, Sándor, János, Ádány, Róza
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier B.V 01.08.2017
• Subjects: Adult; Atherosclerosis - ethnology; Atherosclerosis - genetics; Cardiovascular; Cardiovascular Diseases - ethnology; Cardiovascular Diseases - genetics; Cholesterol, HDL - blood; Cross-Sectional Studies; Female; Gene Frequency; Genetic Predisposition to Disease - ethnology; Genetic risk score; Genetic susceptibility; Genotype; High-density lipoprotein cholesterol; Humans; Hungary - ethnology; Male; Middle Aged; Models, Statistical; Polymorphism, Single Nucleotide; Prevalence; Risk Factors; Roma - genetics; Roma population; Single nucleotide polymorphism; Young Adult; Roma population; Single nucleotide polymorphism; Genetic susceptibility; High-density lipoprotein cholesterol; Genetic risk score

Previous findings showed that reduced plasma high-density lipoprotein cholesterol (HDL-C) levels are more frequent in all age groups of the Hungarian Roma compared to the general population. It suggests that genetic factors may exist behind this phenomenon. Our present study was designed to test thi...