The Academic–Industrial Complexity: Failure to Launch

• Published in: Trends in pharmacological sciences (Regular ed.) Vol. 38; no. 12; pp. 1052 - 1060
• Main Authors: Levin, Leonard A., Behar-Cohen, Francine
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.12.2017
• Subjects: Academies and Institutes - ethics; Academies and Institutes - organization & administration; Animals; bench to bedside; drug development; Drug Discovery; Drug Industry - ethics; Drug Industry - organization & administration; Humans; translational failure; Translational Medical Research - ethics; Translational Medical Research - organization & administration; drug development; translational failure; bench to bedside

The pharmaceutical industry has long known that ∼80% of the results of academic laboratories cannot be reproduced when repeated in industry laboratories. Yet academic investigators are typically unaware of this problem, which severely impedes the drug development process. This academic–industrial co...