Methylophiopogonanone A suppresses ischemia/ reperfusion-induced myocardial apoptosis in mice via activating PI3K/Akt/eNOS signaling pathway - He, Fei; Xu, Bang-long; Chen, Cai; Jia, Hong-jing; Wu, Ji-xiong; Wang, Xiao-chen; Sheng, Jian-long; Huang, Li; Cheng, Jing (Acta pharmacologica Sinica, 2016)
Keywords: Animals; Apoptosis - drug effects; Benzodioxoles - chemistry; Benzodioxoles - therapeutic use; Biomedical and Life Sciences; Biomedicine; Cardiotonic Agents - chemistry; Cardiotonic Agents - therapeutic use; caspase-3; Cell Line; Enzyme Activation - drug effects; Heart - drug effects; Immunology; Internal Medicine; Isoflavones - chemistry; Isoflavones - therapeutic use; Male; Medical Microbiology; Mice; Mice, Inbred C57BL; Myocardial Reperfusion Injury - drug therapy; Myocardial Reperfusion Injury - metabolism; Myocardial Reperfusion Injury - pathology; Myocardium - metabolism; Myocardium - pathology; Nitric Oxide Synthase Type III - metabolism; Ophiopogon - chemistry; Original; original-article; Pharmacology/Toxicology; Phosphatidylinositol 3-Kinases - metabolism; Proto-Oncogene Proteins c-akt - metabolism; Rats; Signal Transduction - drug effects; Vaccine; 信号通路; 心肌细胞凋亡; 激活; 缺血再灌注; 诱导; 麦冬; 黄烷酮; ischemia/reperfusion; wortmannin; eNOS; methylophiopogonanone A; H9C2 rat cardiomyocytes; cardio-protection; apoptosis; coronary heart disease; PI3K/Akt