Demographic and pathogen characteristics of incident bacterial meningitis in infants in South Africa: A cohort study

• Published in: PloS one Vol. 19; no. 9; p. e0310528
• Main Authors: Kiakuvue, Yannick Nkiambi, Mall, Sumaya, Govender, Nelesh, Gottberg, Anne von, Mashau, Rudzani, Meiring, Susan, Cohen, Cheryl
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 25.09.2024
• Subjects: Acinetobacter baumannii; Acinetobacter baumannii - isolation & purification; Acinetobacter baumannii - pathogenicity; Age; Age groups; Analysis; Bacteria; Bacteria, Pathogenic; Bacterial meningitis; Bacterial pneumonia; Biology and Life Sciences; Causes of; Cerebrospinal fluid; Children; Cohort Studies; Culture; Demographic aspects; Demographics; Demography; Diseases; Epidemics; Etiology; Female; Haemophilus influenzae; Haemophilus Vaccines; Humans; Hygiene; Identification and classification; Immunization; Incidence; Infant; Infant, Newborn; Infants; Infants (Newborn); Klebsiella; Klebsiella pneumoniae; Klebsiella pneumoniae - isolation & purification; Klebsiella pneumoniae - pathogenicity; Laboratories; Male; Medicine and Health Sciences; Meningitis; Meningitis, Bacterial - epidemiology; Meningitis, Bacterial - microbiology; Neonates; Nosocomial infection; Pathogens; Pediatric research; People and places; Pneumococcal Vaccines; Pneumonia; Population; Population studies; Risk assessment; South Africa - epidemiology; Statistics; Streptococcus infections; Streptococcus pneumoniae; Streptococcus pneumoniae - isolation & purification; Streptococcus pneumoniae - pathogenicity; Vaccination; Vaccines; Warehouse stores; South Africa; United States > US

Bacterial meningitis is a major cause of death, with an approximate case fatality rate of 37% across all age groups in South Africa. This study aimed to describe the demographic and pathogen characteristics of incident meningitis in children aged <1 year in South Africa from 2014 through 2018, du...