The unfulfilled potential of mucosal immunization

• Published in: Journal of allergy and clinical immunology Vol. 150; no. 1; pp. 1 - 11
• Main Authors: Baker, James R., Farazuddin, Mohammad, Wong, Pamela T., O’Konek, Jessica J.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.07.2022; The Authors. Published by Elsevier Inc. on behalf of the American Academy of Allergy, Asthma & Immunology
• Subjects: barriers to mucosal immunization; Humans; Immunity, Mucosal; Immunization - methods; innate lymphoid cells; Mucosal vaccines; Mucous Membrane; respiratory infections; sterile immunity; tissue resident memory cells; Vaccination - methods; Vaccines; ILC; Mucosal vaccines; sterile immunity; innate lymphoid cells; TRM cell; respiratory infections; COVID-19; ILC2; ILC3; PAMP; SARS-CoV-2; ILC1; tissue resident memory cells; APC; RSV; barriers to mucosal immunization; DC

Recent events involving the global coronavirus pandemic have focused attention on vaccination strategies. Although tremendous advances have been made in subcutaneous and intramuscular vaccines during this time, one area that has lagged in implementation is mucosal immunization. Mucosal immunization...