Toxicity and QSAR of chlorophenols on Lebistes reticulatus

The 24-h toxicity of 20 substituted chlorophenols upon Lebistes reticulatus has been determined. The biological results have been tentatively connected with several of the following six parameters: logarithm of the octanol-water partition coefficient (log P); index of molecular connectivity (1 chi v...

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Bibliographic Details
Published inEcotoxicology and environmental safety Vol. 8; no. 3; p. 227
Main Authors Benoit-Guyod, J L, Andre, C, Taillandier, G, Rochat, J, Boucherle, A
Format Journal Article
LanguageEnglish
Published Netherlands 01.06.1984
Subjects
Animals
Chlorophenols - toxicity
Computers
Female
Fishes
Lethal Dose 50
Male
Regression Analysis
Structure-Activity Relationship
Water Pollutants - toxicity
Water Pollutants, Chemical - toxicity
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Summary:The 24-h toxicity of 20 substituted chlorophenols upon Lebistes reticulatus has been determined. The biological results have been tentatively connected with several of the following six parameters: logarithm of the octanol-water partition coefficient (log P); index of molecular connectivity (1 chi v); molecular refraction (RM); perimeter of the efficient section of the molecule (sigma D); constants of HAMMET (sigma); and melting point (F). A correlation is achieved using sigma D and sigma D2 with a correlation coefficient of 0.943.
ISSN:0147-6513
DOI:10.1016/0147-6513(84)90026-5