Novel PET and Near Infrared Imaging Probes for the Specific Detection of Bacterial Infections Associated With Cardiac Devices - Takemiya, Kiyoko; Ning, Xinghai; Seo, Wonewoo; Wang, Xiaojian; Mohammad, Rafi; Joseph, Giji; Titterington, Jane S.; Kraft, Colleen S.; Nye, Jonathan A.; Murthy, Niren; Goodman, Mark M.; Taylor, W. Robert (JACC. Cardiovascular imaging, 2019)
Keywords: Animals; bacterial imaging; Disease Models, Animal; Early Diagnosis; Fluorescent Dyes - administration & dosage; Fluorescent Dyes - pharmacokinetics; Fluorine Radioisotopes - administration & dosage; Fluorine Radioisotopes - pharmacokinetics; Injections, Intravenous; Male; medical device infections; Oligosaccharides - administration & dosage; Oligosaccharides - pharmacokinetics; optical imaging; Optical Imaging - methods; PET; Positron-Emission Tomography; Predictive Value of Tests; Prosthesis-Related Infections - diagnostic imaging; Prosthesis-Related Infections - microbiology; Radiopharmaceuticals - administration & dosage; Radiopharmaceuticals - pharmacokinetics; Rats, Sprague-Dawley; Reproducibility of Results; Spectroscopy, Near-Infrared; Staphylococcal Infections - diagnostic imaging; Staphylococcal Infections - microbiology; Staphylococcus aureus - growth & development; Staphylococcus aureus - metabolism; Time Factors; MSSA; bacterial imaging; CFU; LB broth; POD; SUV; optical imaging; FDG; medical device infections; CIEDs; ROI; PET