Wheat Gluten Regulates Cholesterol Metabolism by Modulating Gut Microbiota in Hamsters with Hyperlipidemia

• Published in: Journal of Oleo Science Vol. 68; no. 9; pp. 909 - 922
• Main Authors: Liang, Ting-ting, Tong, Li-tao, Geng, Dong-hui, Wang, Li-li, Zhou, Xian-rong, Pu, Hua-yin, Jia, Wei, Wu, Qing-ping, Huang, Jun-rong
• Format: Journal Article
• Language: English
• Published: Japan Japan Oil Chemists' Society 2019; Japan Science and Technology Agency
• Subjects: Abundance; Animals; Anticholesteremic Agents - pharmacology; Bile; Casein; Cholesterol; cholesterol metabolism; Cholesterol, LDL - blood; Cholesterol, LDL - metabolism; Fatty acids; Fatty Acids, Volatile - metabolism; Feces - microbiology; Gastrointestinal Microbiome - drug effects; Gastrointestinal Microbiome - genetics; Gene sequencing; Gluten; Glutens - pharmacology; gut microbiota; Hamsters; Hyperlipidemias - microbiology; hypocholesterolemia; Lipids; Male; Mesocricetus; Metabolism; Microbiota; RNA, Ribosomal, 16S - analysis; Triglycerides; Triticum - chemistry; Wheat; wheat gluten; wheat gluten; hypocholesterolemia; cholesterol metabolism; gut microbiota

The objective of this research was to evaluate the effect of wheat gluten on gut microbiota from hamsters and also analyse whether alterations in microbiota could result in wheat gluten’s lipid-lowering properties. Four weeks male hamsters were divided into 3 groups (n=10). Two hypercholesterolemic...