Advanced fibrosis associates with atherosclerosis in subjects with nonalcoholic fatty liver disease

• Published in: Atherosclerosis Vol. 241; no. 1; pp. 145 - 150
• Main Authors: Chen, Ying, Xu, Min, Wang, Tiange, Sun, Jichao, Sun, Wanwan, Xu, Baihui, Huang, Xiaolin, Xu, Yu, Lu, Jieli, Li, Xiaoying, Wang, Weiqing, Bi, Yufang, Ning, Guang
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier Ireland Ltd 01.07.2015
• Subjects: Aged; Ankle Brachial Index; Atherosclerosis; Brachial-ankle pulse wave velocity; Cardiovascular; Carotid Arteries - diagnostic imaging; Carotid Artery Diseases - complications; Carotid Artery Diseases - diagnosis; Carotid Intima-Media Thickness; Carotid plaque; Chi-Square Distribution; Cross-Sectional Studies; Female; Fibrosis score; Humans; Liver Cirrhosis - diagnosis; Liver Cirrhosis - etiology; Male; Middle Aged; Multivariate Analysis; Non-alcoholic Fatty Liver Disease - complications; Non-alcoholic Fatty Liver Disease - diagnosis; Nonalcoholic fatty liver disease; Odds Ratio; Peripheral Arterial Disease - complications; Peripheral Arterial Disease - diagnosis; Peripheral Arterial Disease - physiopathology; Plaque, Atherosclerotic; Risk Factors; Severity of Illness Index; Vascular Stiffness; Carotid plaque; Nonalcoholic fatty liver disease; Fibrosis score; Brachial-ankle pulse wave velocity; Atherosclerosis; Carotid intima-media thickness

Nonalcoholic fatty liver (NAFLD) with advanced fibrosis usually has a deteriorated prognosis, which was mainly attributed to cardiovascular cause. We investigated whether advanced fibrosis assessed by noninvasive fibrosis markers was associated with subclinical atherosclerosis in NAFLD patients. A t...