Uncovering DNA-PKcs ancient phylogeny, unique sequence motifs and insights for human disease - Lees-Miller, James P.; Cobban, Alexander; Katsonis, Panagiotis; Bacolla, Albino; Tsutakawa, Susan E.; Hammel, Michal; Meek, Katheryn; Anderson, Dave W.; Lichtarge, Olivier; Tainer, John A.; Lees-Miller, Susan P. (Progress in biophysics and molecular biology, 2021)
Keywords: BASIC BIOLOGICAL SCIENCES; Cryo-electron microscopy; Crystal structure; DNA - metabolism; DNA damage Response; DNA repair; DNA-Activated Protein Kinase - genetics; DNA-Activated Protein Kinase - metabolism; DNA-Binding Proteins - metabolism; Humans; Kinase; Motifs; Nuclear Proteins - metabolism; Phosphorylation; Phylogeny; Sequence analysis; Motifs; Kinase; Sequence analysis; DNA repair; DNA damage Response; Cryo-electron microscopy; Crystal structure