Long-term outcomes of autoimmune pancreatitis

Autoimmune pancreatitis(AIP) has been considered a favorable-prognosis disease; however,currently,there is limited information on natural course of AIP during long-term follow-up. Recently published studies regarding the long-term outcomes of AIP has demonstrated the developments of pancreatic stone...

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Published inWorld journal of gastroenterology : WJG Vol. 22; no. 34; pp. 7760 - 7766
Main Authors Ikeura, Tsukasa, Miyoshi, Hideaki, Shimatani, Masaaki, Uchida, Kazushige, Takaoka, Makoto, Okazaki, Kazuichi
Format Journal Article
LanguageEnglish
Published United States Baishideng Publishing Group Inc 14.09.2016
Subjects
Autoimmune
Autoimmune Diseases - complications
Autoimmune Diseases - therapy
Chronic Disease
Disease Progression
Humans
Minireviews
Pancreatic Neoplasms - diagnosis
Pancreatic Neoplasms - pathology
Pancreatic Neoplasms - therapy
Pancreatitis, Chronic - complications
Pancreatitis, Chronic - therapy
pancreatitis;Outcome;Cancer;Prognosis
Prognosis
Recurrence
Steroids - therapeutic use
Treatment Outcome
Prognosis
Autoimmune pancreatitis
Outcome
Cancer
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Summary:Autoimmune pancreatitis(AIP) has been considered a favorable-prognosis disease; however,currently,there is limited information on natural course of AIP during long-term follow-up. Recently published studies regarding the long-term outcomes of AIP has demonstrated the developments of pancreatic stone formation,exocrine insufficiency,and endocrine insufficiency are observed in 5%-41%,34%-82%,and 38%-57% of patients having the disease. Furthermore,the incidence rate of developing pancreatic cancer ranges from 0% to 4.8% during the long-term followup. The event of death from AIP-related complications other than accompanying cancer is likely to be rare. During follow-up of AIP patients,careful surveillance for not only relapse of the disease but also development of complications at regular intervals is needed.
Bibliography:Tsukasa Ikeura;Hideaki Miyoshi;Masaaki Shimatani;Kazushige Uchida;Makoto Takaoka;Kazuichi Okazaki;Department of Gastroenterology and Hepatology,Kansai Medical University
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Telephone: +81-72-8040101 Fax: +81-72-8042534
Author contributions: Ikeura T, Miyoshi H and Shimatani M wrote the manuscript; Uchida K and Takaoka M made revision of the manuscript; Okazaki K made final approval of the manuscript to be published.
Correspondence to: Tsukasa Ikeura, MD, PhD, Department of Gastroenterology and Hepatology, Kansai Medical University, 2-3-1, Shinmachi, Hirakata, Osaka 573-1010, Japan. ikeurat@hirakata.kmu.ac.jp
ISSN:1007-9327
2219-2840
DOI:10.3748/wjg.v22.i34.7760