Platelet tissue factor activity and membrane cholesterol are increased in hypercholesterolemia and normalized by rosuvastatin, but not by atorvastatin - Panes, Olga; González, César; Hidalgo, Patricia; Valderas, Juan P.; Acevedo, Mónica; Contreras, Susana; Sánchez, Ximena; Pereira, Jaime; Rigotti, Attilio; Mezzano, Diego (Atherosclerosis, 2017)
Keywords: Adult; Aged; Atorvastatin Calcium - therapeutic use; Biomarkers - blood; Blood Coagulation - drug effects; Blood Platelets - drug effects; Blood Platelets - metabolism; Cardiovascular; Cell Membrane - drug effects; Cell Membrane - genetics; Chile; Cholesterol - blood; Cholesterol, HDL - blood; Coagulation; Factor Xa - metabolism; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use; Hypercholesterolemia; Hypercholesterolemia - blood; Hypercholesterolemia - diagnosis; Hypercholesterolemia - drug therapy; Male; Middle Aged; Platelet Aggregation - drug effects; Platelet Glycoprotein GPIb-IX Complex - metabolism; Platelets; Rosuvastatin Calcium - therapeutic use; Statins; Thromboplastin - metabolism; Thrombosis; Time Factors; Tissue factor; Treatment Outcome; Hypercholesterolemia; Platelets; Thrombosis; Statins; Tissue factor; Coagulation