Blood clots and bleeding events following BNT162b2 and ChAdOx1 nCoV-19 vaccine: An analysis of European data

• Published in: Journal of autoimmunity Vol. 122; p. 102685
• Main Authors: Cari, Luigi, Fiore, Paolo, Naghavi Alhosseini, Mahdieh, Sava, Gianni, Nocentini, Giuseppe
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.08.2021; The Authors. Published by Elsevier Ltd
• Subjects: Adolescent; Adult; Anti-CoViD-19 vaccines; BNT162 Vaccine; ChAdOx1 nCoV-19; COVID-19 - prevention & control; COVID-19 Vaccines - adverse effects; Europe; Female; Hemorrhage - epidemiology; Hemorrhage - etiology; Humans; Male; Middle Aged; Risk factors; SARS-CoV-2; Severe adverse events; Thrombocytopenia; Thrombocytopenia - epidemiology; Thrombocytopenia - etiology; Thrombosis - epidemiology; Thrombosis - etiology; Venous thrombosis; Young Adult; Europe; Thrombocytopenia; Venous thrombosis; Anti-CoViD-19 vaccines; Risk factors; Severe adverse events

The involvement of viruses and SARS-CoV-2 in autoimmune diseases is well known. The recent demonstration that ChAdOx1 nCoV-19 Covid-19 (AstraZeneca) vaccine (ChA) favors the production of anti-platelet factor 4 (anti-PF4) antibodies, blood clots, and thrombocytopenia raises the question of whether o...