Discovery of a Novel Polymer for Xeno‐Free, Long‐Term Culture of Human Pluripotent Stem Cell Expansion

• Published in: Advanced healthcare materials Vol. 10; no. 6; pp. e2001448 - n/a
• Main Authors: Nasir, Aishah, Thorpe, Jordan, Burroughs, Laurence, Meurs, Joris, Pijuan‐Galito, Sara, Irvine, Derek J., Alexander, Morgan R., Denning, Chris
• Format: Journal Article
• Language: English
• Published: Germany 01.03.2021
• Subjects: biomaterials discovery; Cell Culture Techniques; Cell Differentiation; Cell Proliferation; Essential 8 medium; human pluripotent stem cells; Humans; Pluripotent Stem Cells; polymer microarrays; Polymers; Reproducibility of Results; xeno‐free conditions; biomaterials discovery; human pluripotent stem cells; xeno-free conditions; Essential 8 medium; polymer microarrays

Human pluripotent stem cells (hPSCs) can be expanded and differentiated in vitro into almost any adult tissue cell type, and thus have great potential as a source for cell therapies with biomedical application. In this study, a fully‐defined polymer synthetic substrate is identified for hPSC culture...