Pre‐oxygenation and apnoea in pregnancy: changes during labour and with obstetric morbidity in a computational simulation

• Published in: Anaesthesia Vol. 64; no. 4; pp. 371 - 377
• Main Authors: McClelland, S. H., Bogod, D. G., Hardman, J. G.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.04.2009; Wiley-Blackwell
• Subjects: Anesthesia; Anesthesia, General - methods; Anesthesia, Obstetrical - methods; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Apnea - blood; Biological and medical sciences; Body Mass Index; Cesarean Section; Childbirth & labor; Computer Simulation; Female; Humans; Labor, Obstetric - blood; Medical procedures; Medical sciences; Models, Biological; Morbidity; Obesity, Morbid - blood; Obesity, Morbid - complications; Oxygen; Oxygen - blood; Oxygen Inhalation Therapy - methods; Partial Pressure; Pre-Eclampsia - blood; Pregnancy; Pregnancy Complications - blood; Sepsis - blood; Simulation; Pregnancy; Anesthesia; Simulation; Oxygenation; Obstetrics; Morbidity

Summary Using the Nottingham Physiology Simulator, we investigated the effects on pre‐oxygenation and apnoea during rapid sequence induction of labour, obesity, sepsis, pre‐eclampsia, maternal haemorrhage and multiple pregnancy in term pregnancy. Pre‐oxygenation with 100% oxygen was followed by simu...